@inproceedings{c8c90610cbca48ee9ca6c4259e246bf2,
title = "Photobiomodulation by low power laser irradiation involves activation of latent TGF-β1",
abstract = "Laser mediated stimulation of biological process was amongst its very first effects documented by Mester et al. but the ambiguous and tissue-cell context specific biological effects of laser radiation is now termed 'Photobiomodulation'. We found many parallels between the reported biological effects of lasers and a multifaceted growth factor, Transforming Growth Factor-β (TGF-β). This review outlines the interesting parallels between the two fields and our rationale for pursuing their potential causal correlation. We explored this correlation using an in vitro assay systems and a human clinical trial on healing wound extraction sockets that we reported in a recent publication. In conclusion we report that low power laser irradiation can activate latent TGF-β1 and β3 complexes and suggest that this might be one of the major modes of the photobiomodulatory effects of low power lasers.",
keywords = "Laser medicine, Latent-TGF-beta1 activation, Low power laser therapy, Oral wounds, Photobiomodulation, Redox sensing, Wound healing",
author = "Arany, \{Praveen R.\}",
year = "2008",
doi = "10.1007/978-0-387-71809-5\_19",
language = "English",
isbn = "9780387718088",
series = "Lecture Notes in Electrical Engineering",
pages = "207--212",
booktitle = "Proceedings of Light-Activated Tissue Regeneration and Therapy Conference",
note = "2nd Conference on {"}Light-Activated Tissue Regeneration and Therapy{"} an Engineering Conference International, ECI 2007 ; Conference date: 24-06-2007 Through 29-06-2007",
}