Phosphorylation of nuclear matrix proteins in isolated regenerating rat liver nuclei

Steven L. Allen; Ronald Berezney; Donald S. Coffey

doi:10.1016/0006-291X(77)91296-7

Phosphorylation of nuclear matrix proteins in isolated regenerating rat liver nuclei

Steven L. Allen
, Ronald Berezney
, Donald S. Coffey

Biological Sciences

The James Buchanan Brady Laboratory for Reproductive Biology

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

The phosphorylation of nuclear matrix proteins from normal and regenerating rat liver nuclei was examined using an in vitro system of isolated nuclei and γ-³²P-ATP. Phosphorylation of the nuclear matrix proteins was 2-3 fold higher than that of the total nuclear proteins in normal nuclei. The level of phosphorylation of the matrix proteins was enhanced an additional three fold at a period in liver regeneration (12 hours) just preceding the onset of DNA synthesis.

Original language	English
Pages (from-to)	111-116
Number of pages	6
Journal	Biochemical and Biophysical Research Communications
Volume	75
Issue number	1
DOIs	https://doi.org/10.1016/0006-291X(77)91296-7
State	Published - Mar 7 1977

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title = "Phosphorylation of nuclear matrix proteins in isolated regenerating rat liver nuclei",

abstract = "The phosphorylation of nuclear matrix proteins from normal and regenerating rat liver nuclei was examined using an in vitro system of isolated nuclei and γ-32P-ATP. Phosphorylation of the nuclear matrix proteins was 2-3 fold higher than that of the total nuclear proteins in normal nuclei. The level of phosphorylation of the matrix proteins was enhanced an additional three fold at a period in liver regeneration (12 hours) just preceding the onset of DNA synthesis.",

author = "Allen, \{Steven L.\} and Ronald Berezney and Coffey, \{Donald S.\}",

year = "1977",

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T1 - Phosphorylation of nuclear matrix proteins in isolated regenerating rat liver nuclei

AU - Allen, Steven L.

AU - Berezney, Ronald

AU - Coffey, Donald S.

PY - 1977/3/7

Y1 - 1977/3/7

N2 - The phosphorylation of nuclear matrix proteins from normal and regenerating rat liver nuclei was examined using an in vitro system of isolated nuclei and γ-32P-ATP. Phosphorylation of the nuclear matrix proteins was 2-3 fold higher than that of the total nuclear proteins in normal nuclei. The level of phosphorylation of the matrix proteins was enhanced an additional three fold at a period in liver regeneration (12 hours) just preceding the onset of DNA synthesis.

AB - The phosphorylation of nuclear matrix proteins from normal and regenerating rat liver nuclei was examined using an in vitro system of isolated nuclei and γ-32P-ATP. Phosphorylation of the nuclear matrix proteins was 2-3 fold higher than that of the total nuclear proteins in normal nuclei. The level of phosphorylation of the matrix proteins was enhanced an additional three fold at a period in liver regeneration (12 hours) just preceding the onset of DNA synthesis.

UR - https://www.scopus.com/pages/publications/0017338323

U2 - 10.1016/0006-291X(77)91296-7

DO - 10.1016/0006-291X(77)91296-7

M3 - Article

C2 - 849299

AN - SCOPUS:0017338323

SN - 0006-291X

VL - 75

SP - 111

EP - 116

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

IS - 1

ER -

Phosphorylation of nuclear matrix proteins in isolated regenerating rat liver nuclei

Abstract

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