Phosphatidylethanol and Alcohol Use in Liver Disease Patients

Scott H. Stewart

doi:10.1007/978-94-007-7742-2_18-1

Phosphatidylethanol and Alcohol Use in Liver Disease Patients

Scott H. Stewart

Family Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Alcohol use can potentiate liver diseases such as hepatitis C and in sufficient quantities can itself cause significant liver disease over time. This chapter will briefly review the importance of alcohol use in liver diseases and difficulties that can arise when clinicians attempt to gather an accurate drinking history in patients with liver disease. The bulk of the chapter focuses on the use of blood phosphatidylethanol (PEth) as an alcohol consumption biomarker in liver disease patients, including validation in this population, potential uses in clinical care and research, and current limitations to its use for these purposes.

Original language	English
Journal	Exposure and Health
Volume	2016
DOIs	https://doi.org/10.1007/978-94-007-7742-2_18-1
State	Published - 2016

Keywords

Alcohol drinking
Liver disease
Phosphatidylethanol
Sensitivity
Specificity

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10.1007/978-94-007-7742-2_18-1

Cite this

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abstract = "Alcohol use can potentiate liver diseases such as hepatitis C and in sufficient quantities can itself cause significant liver disease over time. This chapter will briefly review the importance of alcohol use in liver diseases and difficulties that can arise when clinicians attempt to gather an accurate drinking history in patients with liver disease. The bulk of the chapter focuses on the use of blood phosphatidylethanol (PEth) as an alcohol consumption biomarker in liver disease patients, including validation in this population, potential uses in clinical care and research, and current limitations to its use for these purposes.",

keywords = "Alcohol drinking, Liver disease, Phosphatidylethanol, Sensitivity, Specificity",

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N1 - Publisher Copyright: © Springer Science+Business Media Dordrecht 2016.

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N2 - Alcohol use can potentiate liver diseases such as hepatitis C and in sufficient quantities can itself cause significant liver disease over time. This chapter will briefly review the importance of alcohol use in liver diseases and difficulties that can arise when clinicians attempt to gather an accurate drinking history in patients with liver disease. The bulk of the chapter focuses on the use of blood phosphatidylethanol (PEth) as an alcohol consumption biomarker in liver disease patients, including validation in this population, potential uses in clinical care and research, and current limitations to its use for these purposes.

AB - Alcohol use can potentiate liver diseases such as hepatitis C and in sufficient quantities can itself cause significant liver disease over time. This chapter will briefly review the importance of alcohol use in liver diseases and difficulties that can arise when clinicians attempt to gather an accurate drinking history in patients with liver disease. The bulk of the chapter focuses on the use of blood phosphatidylethanol (PEth) as an alcohol consumption biomarker in liver disease patients, including validation in this population, potential uses in clinical care and research, and current limitations to its use for these purposes.

KW - Alcohol drinking

KW - Liver disease

KW - Phosphatidylethanol

KW - Sensitivity

KW - Specificity

UR - https://www.scopus.com/pages/publications/85137697406

U2 - 10.1007/978-94-007-7742-2_18-1

DO - 10.1007/978-94-007-7742-2_18-1

M3 - Article

AN - SCOPUS:85137697406

SN - 2451-9766

VL - 2016

JO - Exposure and Health

JF - Exposure and Health

ER -

Phosphatidylethanol and Alcohol Use in Liver Disease Patients

Abstract

Keywords

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