Pharmacokinetics and Drug Design

Ho Leung Fung; Bruce J. Aungst; Richard A. Morrison

doi:10.1016/S0065-7743(08)61375-5

Pharmacokinetics and Drug Design

Ho Leung Fung
, Bruce J. Aungst
, Richard A. Morrison

Pharmaceutical Sciences

SUNY Buffalo

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

It has been shown that pharmacokinetic parameters can be favorably affected by structural modification without, incertain cases, alteration in the pharmacological properties of the parent drug. Detailed pharmacokinetic information obtained for lead compounds may provide a valuable guide as to how subsequent syntheses should be directed.

Original language	English
Pages (from-to)	309-320
Number of pages	12
Journal	Annual Reports in Medicinal Chemistry
Volume	14
Issue number	C
DOIs	https://doi.org/10.1016/S0065-7743(08)61375-5
State	Published - Jan 1 1979

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title = "Pharmacokinetics and Drug Design",

abstract = "It has been shown that pharmacokinetic parameters can be favorably affected by structural modification without, incertain cases, alteration in the pharmacological properties of the parent drug. Detailed pharmacokinetic information obtained for lead compounds may provide a valuable guide as to how subsequent syntheses should be directed.",

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AU - Aungst, Bruce J.

AU - Morrison, Richard A.

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N2 - It has been shown that pharmacokinetic parameters can be favorably affected by structural modification without, incertain cases, alteration in the pharmacological properties of the parent drug. Detailed pharmacokinetic information obtained for lead compounds may provide a valuable guide as to how subsequent syntheses should be directed.

AB - It has been shown that pharmacokinetic parameters can be favorably affected by structural modification without, incertain cases, alteration in the pharmacological properties of the parent drug. Detailed pharmacokinetic information obtained for lead compounds may provide a valuable guide as to how subsequent syntheses should be directed.

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U2 - 10.1016/S0065-7743(08)61375-5

DO - 10.1016/S0065-7743(08)61375-5

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AN - SCOPUS:77956729335

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VL - 14

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JO - Annual Reports in Medicinal Chemistry

JF - Annual Reports in Medicinal Chemistry

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Pharmacokinetics and Drug Design

Abstract

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