PHARMACODYNAMICS

Beom Soo Shin; Dhavalkumar Shah; Joseph P. Balthasar

doi:10.1002/9780470571224.pse064

PHARMACODYNAMICS

Pharmaceutical Sciences

SUNY Buffalo

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Pharmacodynamics refers to the study of relationships between drug concentrations and pharmacological effects. The mathematical description of these relationships, through the use of appropriate pharmacodynamic models, facilitates the characterization and comparison of candidate drugs, facilitates the rational selection of appropriate dosing regimens, and assists in the investigation and identification of the mechanisms associated with drug action. This article provides an overview and a catalog of mathematical models that may be employed to characterize drug pharmacodynamics.

Original language	English
Title of host publication	Pharmaceutical Sciences Encyclopedia
Publisher	wiley
Pages	1-34
Number of pages	34
ISBN (Electronic)	9780470571224
DOIs	https://doi.org/10.1002/9780470571224.pse064
State	Published - Jan 1 2010

Keywords

drugs
kinetic models
pharmacodynamics
pharmacological response
static models

Access to Document

10.1002/9780470571224.pse064

Cite this

@inbook{00884a5cf4a14e7a96a343ad9ace145e,

title = "PHARMACODYNAMICS",

abstract = "Pharmacodynamics refers to the study of relationships between drug concentrations and pharmacological effects. The mathematical description of these relationships, through the use of appropriate pharmacodynamic models, facilitates the characterization and comparison of candidate drugs, facilitates the rational selection of appropriate dosing regimens, and assists in the investigation and identification of the mechanisms associated with drug action. This article provides an overview and a catalog of mathematical models that may be employed to characterize drug pharmacodynamics.",

keywords = "drugs, kinetic models, pharmacodynamics, pharmacological response, static models",

author = "Shin, \{Beom Soo\} and Dhavalkumar Shah and Balthasar, \{Joseph P.\}",

note = "Publisher Copyright: {\textcopyright} 2010 John Wiley \& Sons, Inc.",

year = "2010",

month = jan,

day = "1",

doi = "10.1002/9780470571224.pse064",

language = "English",

pages = "1--34",

booktitle = "Pharmaceutical Sciences Encyclopedia",

publisher = "wiley",

}

TY - CHAP

T1 - PHARMACODYNAMICS

AU - Shin, Beom Soo

AU - Shah, Dhavalkumar

AU - Balthasar, Joseph P.

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Pharmacodynamics refers to the study of relationships between drug concentrations and pharmacological effects. The mathematical description of these relationships, through the use of appropriate pharmacodynamic models, facilitates the characterization and comparison of candidate drugs, facilitates the rational selection of appropriate dosing regimens, and assists in the investigation and identification of the mechanisms associated with drug action. This article provides an overview and a catalog of mathematical models that may be employed to characterize drug pharmacodynamics.

AB - Pharmacodynamics refers to the study of relationships between drug concentrations and pharmacological effects. The mathematical description of these relationships, through the use of appropriate pharmacodynamic models, facilitates the characterization and comparison of candidate drugs, facilitates the rational selection of appropriate dosing regimens, and assists in the investigation and identification of the mechanisms associated with drug action. This article provides an overview and a catalog of mathematical models that may be employed to characterize drug pharmacodynamics.

KW - drugs

KW - kinetic models

KW - pharmacodynamics

KW - pharmacological response

KW - static models

UR - https://www.scopus.com/pages/publications/105031344698

U2 - 10.1002/9780470571224.pse064

DO - 10.1002/9780470571224.pse064

M3 - Chapter

AN - SCOPUS:105031344698

SP - 1

EP - 34

BT - Pharmaceutical Sciences Encyclopedia

PB - wiley

ER -

PHARMACODYNAMICS

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this