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Pediatric lymphomas and histiocytic disorders of childhood

  • Baylor College of Medicine
  • George Washington University

Research output: Contribution to journalReview articlepeer-review

85 Scopus citations

Abstract

Although there have been dramatic improvements in the treatment of children with non-hodgkin lymphoma, hodgkin lymphoma and histiocytic disorders over the past 3 decades, many still relapse or are refractory to primary therapy. In addition, late effects such as 2nd malignancies, cardiomyopathy and infertility remain a major concern. Thus, this review focuses on the current state of the science and, in particular, novel treatment strategies that are aimed at improving outcomes for all pediatric patients with lymphoma and histiocytic disorders while reducing treatment related morbidity.

Original languageEnglish
Pages (from-to)139-165
Number of pages27
JournalPediatric Clinics of North America
Volume62
Issue number1
DOIs
StatePublished - Feb 1 2015

Keywords

  • Anaplastic large cell lymphoma (ALCL)
  • Burkitt lymphoma (BL)
  • Diffuse large B-cell lymphoma (DLBCL)
  • Hodgkin lymphoma (HL)
  • Juvenile xanthoganuloma (JXG)
  • Langerhans cell histiocytosis (LCH)
  • Posttransplant lymphoproliferative disease (PTLD)
  • Rosai-Dorfman disease (RDD)

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