Pediatric Acute Lymphoblastic Leukemia, Version 2.2025

Hiroto Inaba; David Teachey; Colleen Annesley; Sandeep Batra; Jill Beck; Susan Colace; Stacy Cooper; Mari Dallas; Satiro De Oliveira; Kara Kelly; Carrie Kitko; Mira Kohorst; Matthew Kutny; Norman Lacayo; Cathy Lee-Miller; Kathleen Ludwig; Lisa Madden; Kelly Maloney; David Mangum; Stephanie Massaro; David McCall; Perry Morocco; Brad Muller; Lindsey Murphy; Valentina Nardi; Jenna Rossoff; Laura Schuettpelz; Bijal Shah; Jessica Sun; Victor Wong; Gregory Yanik; Ajibola Awotiwon; Katie Stehman

doi:10.6004/jnccn.2025.0006

Pediatric Acute Lymphoblastic Leukemia, Version 2.2025

Hiroto Inaba
, David Teachey
, Colleen Annesley
, Sandeep Batra
, Jill Beck
, Susan Colace
, Stacy Cooper
, Mari Dallas
, Satiro De Oliveira
, Kara Kelly
, Carrie Kitko
, Mira Kohorst
, Matthew Kutny
, Norman Lacayo
, Cathy Lee-Miller
, Kathleen Ludwig
, Lisa Madden
, Kelly Maloney
, David Mangum
, Stephanie Massaro

David McCall, Perry Morocco, Brad Muller, Lindsey Murphy, Valentina Nardi, Jenna Rossoff, Laura Schuettpelz, Bijal Shah, Jessica Sun, Victor Wong, Gregory Yanik, Ajibola Awotiwon, Katie Stehman

Pediatrics

University of Tennessee Health Science Center
University of Pennsylvania
Seattle Children's Hospital
Indiana University Bloomington
University of Nebraska Medical Center
Ohio State University
Johns Hopkins University
Case Western Reserve University
University of California at Los Angeles
Vanderbilt University
Mayo Clinic Rochester, MN
University of Alabama at Birmingham
Stanford University
University of Wisconsin-Madison
Children's Medical Center Dallas
University of California at Davis
University of Colorado Anschutz Medical Campus
University of Utah
Yale University
University of Texas MD Anderson Cancer Center
The University of Chicago
City of Hope National Med Center
Dana-Farber Cancer Institute
Northwestern University
Washington University St. Louis
Moffitt Cancer Center
Duke University
Rady Children's Hospital
University of Michigan, Ann Arbor
National Comprehensive Cancer Network

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pediatric Acute Lymphoblastic Leukemia (ALL) were developed as a result of meetings convened by a multidisciplinary panel of pediatric ALL experts, with the goal of providing recommendations on standard treatment approaches based on current evidence. The NCCN Guidelines for pediatric ALL focus on risk assessment and stratification of risk-adapted therapy; treatment strategies for BCR::ABL1 (Philadelphia chromosome [Ph])-negative and BCR::ABL1-positive B-cell lineage, T-cell lineage, and infant ALL; and supportive care considerations. This selection from the NCCN Guidelines for pediatric ALL focuses on the diagnosis of and management of pediatric T-ALL.

Original language	English
Pages (from-to)	41-62
Number of pages	22
Journal	JNCCN Journal of the National Comprehensive Cancer Network
Volume	23
Issue number	2
DOIs	https://doi.org/10.6004/jnccn.2025.0006
State	Published - Feb 2025

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Inaba, H., Teachey, D., Annesley, C., Batra, S., Beck, J., Colace, S., Cooper, S., Dallas, M., De Oliveira, S., Kelly, K., Kitko, C., Kohorst, M., Kutny, M., Lacayo, N., Lee-Miller, C., Ludwig, K., Madden, L., Maloney, K., Mangum, D., ... Stehman, K. (2025). Pediatric Acute Lymphoblastic Leukemia, Version 2.2025. JNCCN Journal of the National Comprehensive Cancer Network, 23(2), 41-62. https://doi.org/10.6004/jnccn.2025.0006

@article{36a7954db23948188d41976815cbdb47,

title = "Pediatric Acute Lymphoblastic Leukemia, Version 2.2025",

abstract = "The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pediatric Acute Lymphoblastic Leukemia (ALL) were developed as a result of meetings convened by a multidisciplinary panel of pediatric ALL experts, with the goal of providing recommendations on standard treatment approaches based on current evidence. The NCCN Guidelines for pediatric ALL focus on risk assessment and stratification of risk-adapted therapy; treatment strategies for BCR::ABL1 (Philadelphia chromosome [Ph])-negative and BCR::ABL1-positive B-cell lineage, T-cell lineage, and infant ALL; and supportive care considerations. This selection from the NCCN Guidelines for pediatric ALL focuses on the diagnosis of and management of pediatric T-ALL.",

author = "Hiroto Inaba and David Teachey and Colleen Annesley and Sandeep Batra and Jill Beck and Susan Colace and Stacy Cooper and Mari Dallas and \{De Oliveira\}, Satiro and Kara Kelly and Carrie Kitko and Mira Kohorst and Matthew Kutny and Norman Lacayo and Cathy Lee-Miller and Kathleen Ludwig and Lisa Madden and Kelly Maloney and David Mangum and Stephanie Massaro and David McCall and Perry Morocco and Brad Muller and Lindsey Murphy and Valentina Nardi and Jenna Rossoff and Laura Schuettpelz and Bijal Shah and Jessica Sun and Victor Wong and Gregory Yanik and Ajibola Awotiwon and Katie Stehman",

year = "2025",

month = feb,

doi = "10.6004/jnccn.2025.0006",

language = "English",

volume = "23",

pages = "41--62",

journal = "JNCCN Journal of the National Comprehensive Cancer Network",

issn = "1540-1405",

publisher = "Harborside Press",

number = "2",

}

Inaba, H, Teachey, D, Annesley, C, Batra, S, Beck, J, Colace, S, Cooper, S, Dallas, M, De Oliveira, S, Kelly, K, Kitko, C, Kohorst, M, Kutny, M, Lacayo, N, Lee-Miller, C, Ludwig, K, Madden, L, Maloney, K, Mangum, D, Massaro, S, McCall, D, Morocco, P, Muller, B, Murphy, L, Nardi, V, Rossoff, J, Schuettpelz, L, Shah, B, Sun, J, Wong, V, Yanik, G, Awotiwon, A & Stehman, K 2025, 'Pediatric Acute Lymphoblastic Leukemia, Version 2.2025', JNCCN Journal of the National Comprehensive Cancer Network, vol. 23, no. 2, pp. 41-62. https://doi.org/10.6004/jnccn.2025.0006

TY - JOUR

T1 - Pediatric Acute Lymphoblastic Leukemia, Version 2.2025

AU - Inaba, Hiroto

AU - Teachey, David

AU - Annesley, Colleen

AU - Batra, Sandeep

AU - Beck, Jill

AU - Colace, Susan

AU - Cooper, Stacy

AU - Dallas, Mari

AU - De Oliveira, Satiro

AU - Kelly, Kara

AU - Kitko, Carrie

AU - Kohorst, Mira

AU - Kutny, Matthew

AU - Lacayo, Norman

AU - Lee-Miller, Cathy

AU - Ludwig, Kathleen

AU - Madden, Lisa

AU - Maloney, Kelly

AU - Mangum, David

AU - Massaro, Stephanie

AU - McCall, David

AU - Morocco, Perry

AU - Muller, Brad

AU - Murphy, Lindsey

AU - Nardi, Valentina

AU - Rossoff, Jenna

AU - Schuettpelz, Laura

AU - Shah, Bijal

AU - Sun, Jessica

AU - Wong, Victor

AU - Yanik, Gregory

AU - Awotiwon, Ajibola

AU - Stehman, Katie

PY - 2025/2

Y1 - 2025/2

N2 - The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pediatric Acute Lymphoblastic Leukemia (ALL) were developed as a result of meetings convened by a multidisciplinary panel of pediatric ALL experts, with the goal of providing recommendations on standard treatment approaches based on current evidence. The NCCN Guidelines for pediatric ALL focus on risk assessment and stratification of risk-adapted therapy; treatment strategies for BCR::ABL1 (Philadelphia chromosome [Ph])-negative and BCR::ABL1-positive B-cell lineage, T-cell lineage, and infant ALL; and supportive care considerations. This selection from the NCCN Guidelines for pediatric ALL focuses on the diagnosis of and management of pediatric T-ALL.

AB - The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pediatric Acute Lymphoblastic Leukemia (ALL) were developed as a result of meetings convened by a multidisciplinary panel of pediatric ALL experts, with the goal of providing recommendations on standard treatment approaches based on current evidence. The NCCN Guidelines for pediatric ALL focus on risk assessment and stratification of risk-adapted therapy; treatment strategies for BCR::ABL1 (Philadelphia chromosome [Ph])-negative and BCR::ABL1-positive B-cell lineage, T-cell lineage, and infant ALL; and supportive care considerations. This selection from the NCCN Guidelines for pediatric ALL focuses on the diagnosis of and management of pediatric T-ALL.

UR - https://www.scopus.com/pages/publications/85217941907

U2 - 10.6004/jnccn.2025.0006

DO - 10.6004/jnccn.2025.0006

M3 - Article

C2 - 39938467

AN - SCOPUS:85217941907

SN - 1540-1405

VL - 23

SP - 41

EP - 62

JO - JNCCN Journal of the National Comprehensive Cancer Network

JF - JNCCN Journal of the National Comprehensive Cancer Network

IS - 2

ER -

Pediatric Acute Lymphoblastic Leukemia, Version 2.2025

Abstract

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