Pangenomes of the human oral microbiome

Julian Torres-Morales; Jonathan J. Giacomini; Tsute Chen; Andrew Voorhis; Kathryn M. Kauffman; Floyd E. Dewhirst; Gary G. Borisy; Jessica L. Mark Welch

doi:10.1128/mra.00261-26

Pangenomes of the human oral microbiome

Julian Torres-Morales
, Jonathan J. Giacomini
, Tsute Chen
, Andrew Voorhis
, Kathryn M. Kauffman
, Floyd E. Dewhirst
, Gary G. Borisy
, Jessica L. Mark Welch

Department of Oral Biology

The Forsyth Institute
The University of Chicago
Harvard University

Research output: Contribution to journal › Article › peer-review

Abstract

We announce the release of 579 pangenomes derived from 8,115 genomes curated by the Human Oral Microbiome Database, capturing shared and variable gene content across oral microbial taxa. This openly accessible resource supports both online and offline exploration, enabling systematic studies of microbial function, evolution, and community structure.

Original language	English
Article number	e00261-26
Journal	Microbiology Resource Announcements
Volume	15
Issue number	7
DOIs	https://doi.org/10.1128/mra.00261-26
State	Published - Jul 2026

Keywords

comparative genomics
human microbiome
large-scale genomics
oral microbiome
pangenomes

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10.1128/mra.00261-26

Cite this

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title = "Pangenomes of the human oral microbiome",

abstract = "We announce the release of 579 pangenomes derived from 8,115 genomes curated by the Human Oral Microbiome Database, capturing shared and variable gene content across oral microbial taxa. This openly accessible resource supports both online and offline exploration, enabling systematic studies of microbial function, evolution, and community structure.",

keywords = "comparative genomics, human microbiome, large-scale genomics, oral microbiome, pangenomes",

author = "Julian Torres-Morales and Giacomini, \{Jonathan J.\} and Tsute Chen and Andrew Voorhis and Kauffman, \{Kathryn M.\} and Dewhirst, \{Floyd E.\} and Borisy, \{Gary G.\} and \{Mark Welch\}, \{Jessica L.\}",

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AU - Giacomini, Jonathan J.

AU - Chen, Tsute

AU - Voorhis, Andrew

AU - Kauffman, Kathryn M.

AU - Dewhirst, Floyd E.

AU - Borisy, Gary G.

AU - Mark Welch, Jessica L.

PY - 2026/7

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AB - We announce the release of 579 pangenomes derived from 8,115 genomes curated by the Human Oral Microbiome Database, capturing shared and variable gene content across oral microbial taxa. This openly accessible resource supports both online and offline exploration, enabling systematic studies of microbial function, evolution, and community structure.

KW - comparative genomics

KW - human microbiome

KW - large-scale genomics

KW - oral microbiome

KW - pangenomes

UR - https://www.scopus.com/pages/publications/105044576182

U2 - 10.1128/mra.00261-26

DO - 10.1128/mra.00261-26

M3 - Article

AN - SCOPUS:105044576182

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VL - 15

JO - Microbiology Resource Announcements

JF - Microbiology Resource Announcements

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ER -

Pangenomes of the human oral microbiome

Abstract

Keywords

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