Orbital involvement as the initial manifestation of sarcoidosis: Magnetic resonance imaging findings

Zubair A. Shaikh; Rohit Bakshi; Steven J. Greenberg; Edward J. Fine; Ahmed Shatla; Norah S. Lincoff

doi:10.1111/jon2000103180

Orbital involvement as the initial manifestation of sarcoidosis: Magnetic resonance imaging findings

Zubair A. Shaikh
, Rohit Bakshi
, Steven J. Greenberg
, Edward J. Fine
, Ahmed Shatla
, Norah S. Lincoff

Neurology

SUNY Buffalo
Neuroscience Center E-2

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

A 74-year-old man had diplopia, painful right ophthalmoplegia, proptosis, conjunctival injection, and facial skin lesions. Magnetic resonance imaging (MRI) revealed infiltration of the right intraorbital adipose tissue. Lesions were mixed low- and high-signal on T2-weighted images and enhanced on fat-suppressed T1-weighted postcontrast images. A skin biopsy revealed numerous noncaseating granulomas consistent with sarcoidosis. Treatment with corticosteroids and chlorambucil led to a full clinical recovery. Sarcoidosis should be considered in the evaluation of orbital pseudotumor in elderly patients, even if no systemic manifestations of sarcoidosis are present.

Original language	English
Pages (from-to)	180-183
Number of pages	4
Journal	Journal of Neuroimaging
Volume	10
Issue number	3
DOIs	https://doi.org/10.1111/jon2000103180
State	Published - 2000

Keywords

Lacrimal gland
Lupus pernio
MRI
Orbit
Orbital pseudotumor
Sarcoidosis

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10.1111/jon2000103180

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title = "Orbital involvement as the initial manifestation of sarcoidosis: Magnetic resonance imaging findings",

abstract = "A 74-year-old man had diplopia, painful right ophthalmoplegia, proptosis, conjunctival injection, and facial skin lesions. Magnetic resonance imaging (MRI) revealed infiltration of the right intraorbital adipose tissue. Lesions were mixed low- and high-signal on T2-weighted images and enhanced on fat-suppressed T1-weighted postcontrast images. A skin biopsy revealed numerous noncaseating granulomas consistent with sarcoidosis. Treatment with corticosteroids and chlorambucil led to a full clinical recovery. Sarcoidosis should be considered in the evaluation of orbital pseudotumor in elderly patients, even if no systemic manifestations of sarcoidosis are present.",

keywords = "Lacrimal gland, Lupus pernio, MRI, Orbit, Orbital pseudotumor, Sarcoidosis",

author = "Shaikh, \{Zubair A.\} and Rohit Bakshi and Greenberg, \{Steven J.\} and Fine, \{Edward J.\} and Ahmed Shatla and Lincoff, \{Norah S.\}",

year = "2000",

doi = "10.1111/jon2000103180",

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journal = "Journal of Neuroimaging",

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TY - JOUR

T1 - Orbital involvement as the initial manifestation of sarcoidosis

T2 - Magnetic resonance imaging findings

AU - Shaikh, Zubair A.

AU - Bakshi, Rohit

AU - Greenberg, Steven J.

AU - Fine, Edward J.

AU - Shatla, Ahmed

AU - Lincoff, Norah S.

PY - 2000

Y1 - 2000

N2 - A 74-year-old man had diplopia, painful right ophthalmoplegia, proptosis, conjunctival injection, and facial skin lesions. Magnetic resonance imaging (MRI) revealed infiltration of the right intraorbital adipose tissue. Lesions were mixed low- and high-signal on T2-weighted images and enhanced on fat-suppressed T1-weighted postcontrast images. A skin biopsy revealed numerous noncaseating granulomas consistent with sarcoidosis. Treatment with corticosteroids and chlorambucil led to a full clinical recovery. Sarcoidosis should be considered in the evaluation of orbital pseudotumor in elderly patients, even if no systemic manifestations of sarcoidosis are present.

AB - A 74-year-old man had diplopia, painful right ophthalmoplegia, proptosis, conjunctival injection, and facial skin lesions. Magnetic resonance imaging (MRI) revealed infiltration of the right intraorbital adipose tissue. Lesions were mixed low- and high-signal on T2-weighted images and enhanced on fat-suppressed T1-weighted postcontrast images. A skin biopsy revealed numerous noncaseating granulomas consistent with sarcoidosis. Treatment with corticosteroids and chlorambucil led to a full clinical recovery. Sarcoidosis should be considered in the evaluation of orbital pseudotumor in elderly patients, even if no systemic manifestations of sarcoidosis are present.

KW - Lacrimal gland

KW - Lupus pernio

KW - MRI

KW - Orbit

KW - Orbital pseudotumor

KW - Sarcoidosis

UR - https://www.scopus.com/pages/publications/0033940010

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DO - 10.1111/jon2000103180

M3 - Article

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AN - SCOPUS:0033940010

SN - 1051-2284

VL - 10

SP - 180

EP - 183

JO - Journal of Neuroimaging

JF - Journal of Neuroimaging

IS - 3

ER -

Orbital involvement as the initial manifestation of sarcoidosis: Magnetic resonance imaging findings

Abstract

Keywords

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