Oral ulcerations in individuals infected with human immunodeficiency virus: Clinical presentations, diagnosis, management, and relevance to disease progression

Oral ulcerations can be both a localized disease entity and a manifestation of an underlying systemic condition. In individuals infected with the human immunodeficiency virus, oral ulceration may serve as a marker for a specific systemic illness, early immunosuppression, and disease progression. This article reviews clinical manifestations, diagnosis, and management of oral ulcerations in individuals with the human immunodeficiency virus.