Opportunities for integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development

Carl C. Peck; William H. Barr; Leslie Z. Benet; Jerry Collins; Robert E. Desjardins; Daniel E. Furst; John G. Harter; Gerhard Levy; Thomas Ludden; John H. Rodman; Lilly Sanathana; Jerome J. Schentag; Vinod P. Shah; Lewis B. Sheiner; Jerome P. Skelly; Donald R. Stanski; Robert J. Temple; C. T. Viswanathan; Judi Weissinger; Avraham Yacobi

doi:10.1038/clpt.1992.47

Opportunities for integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development

Carl C. Peck
, William H. Barr
, Leslie Z. Benet
, Jerry Collins
, Robert E. Desjardins
, Daniel E. Furst
, John G. Harter
, Gerhard Levy
, Thomas Ludden
, John H. Rodman
, Lilly Sanathana
, Jerome J. Schentag
, Vinod P. Shah
, Lewis B. Sheiner
, Jerome P. Skelly
, Donald R. Stanski
, Robert J. Temple
, C. T. Viswanathan
, Judi Weissinger
, Avraham Yacobi

Pharmacy

United States Food and Drug Administration
Virginia Commonwealth University
University of California at San Francisco
American Cyan-amid Co
Ciba-Geigy Pharmaceuticals
SUNY Buffalo
St. Jude Children Research Hospital
VA Medical Center

Research output: Contribution to journal › Article › peer-review

194 Scopus citations

Abstract

Clinical Pharmacology and Therapeutics (1992) 51, 465–473; doi:

Original language	English
Pages (from-to)	465-473
Number of pages	9
Journal	Clinical Pharmacology and Therapeutics
Volume	51
Issue number	4
DOIs	https://doi.org/10.1038/clpt.1992.47
State	Published - Apr 1992

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10.1038/clpt.1992.47

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Peck, C. C., Barr, W. H., Benet, L. Z., Collins, J., Desjardins, R. E., Furst, D. E., Harter, J. G., Levy, G., Ludden, T., Rodman, J. H., Sanathana, L., Schentag, J. J., Shah, V. P., Sheiner, L. B., Skelly, J. P., Stanski, D. R., Temple, R. J., Viswanathan, C. T., Weissinger, J., & Yacobi, A. (1992). Opportunities for integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development. Clinical Pharmacology and Therapeutics, 51(4), 465-473. https://doi.org/10.1038/clpt.1992.47

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title = "Opportunities for integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development",

abstract = "Clinical Pharmacology and Therapeutics (1992) 51, 465–473; doi:",

author = "Peck, \{Carl C.\} and Barr, \{William H.\} and Benet, \{Leslie Z.\} and Jerry Collins and Desjardins, \{Robert E.\} and Furst, \{Daniel E.\} and Harter, \{John G.\} and Gerhard Levy and Thomas Ludden and Rodman, \{John H.\} and Lilly Sanathana and Schentag, \{Jerome J.\} and Shah, \{Vinod P.\} and Sheiner, \{Lewis B.\} and Skelly, \{Jerome P.\} and Stanski, \{Donald R.\} and Temple, \{Robert J.\} and Viswanathan, \{C. T.\} and Judi Weissinger and Avraham Yacobi",

year = "1992",

month = apr,

doi = "10.1038/clpt.1992.47",

language = "English",

volume = "51",

pages = "465--473",

journal = "Clinical Pharmacology and Therapeutics",

issn = "0009-9236",

publisher = "Wiley-Blackwell",

number = "4",

}

Peck, CC, Barr, WH, Benet, LZ, Collins, J, Desjardins, RE, Furst, DE, Harter, JG, Levy, G, Ludden, T, Rodman, JH, Sanathana, L, Schentag, JJ, Shah, VP, Sheiner, LB, Skelly, JP, Stanski, DR, Temple, RJ, Viswanathan, CT, Weissinger, J & Yacobi, A 1992, 'Opportunities for integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development', Clinical Pharmacology and Therapeutics, vol. 51, no. 4, pp. 465-473. https://doi.org/10.1038/clpt.1992.47

TY - JOUR

T1 - Opportunities for integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development

AU - Peck, Carl C.

AU - Barr, William H.

AU - Benet, Leslie Z.

AU - Collins, Jerry

AU - Desjardins, Robert E.

AU - Furst, Daniel E.

AU - Harter, John G.

AU - Levy, Gerhard

AU - Ludden, Thomas

AU - Rodman, John H.

AU - Sanathana, Lilly

AU - Schentag, Jerome J.

AU - Shah, Vinod P.

AU - Sheiner, Lewis B.

AU - Skelly, Jerome P.

AU - Stanski, Donald R.

AU - Temple, Robert J.

AU - Viswanathan, C. T.

AU - Weissinger, Judi

AU - Yacobi, Avraham

PY - 1992/4

Y1 - 1992/4

N2 - Clinical Pharmacology and Therapeutics (1992) 51, 465–473; doi:

AB - Clinical Pharmacology and Therapeutics (1992) 51, 465–473; doi:

UR - https://www.scopus.com/pages/publications/0026504422

U2 - 10.1038/clpt.1992.47

DO - 10.1038/clpt.1992.47

M3 - Article

C2 - 1563216

AN - SCOPUS:0026504422

SN - 0009-9236

VL - 51

SP - 465

EP - 473

JO - Clinical Pharmacology and Therapeutics

JF - Clinical Pharmacology and Therapeutics

IS - 4

ER -

Opportunities for integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development

Abstract

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