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On Minimizing Risk and Harm in the Use of Psychedelics

  • Jules Evans
  • , Marc Aixalà
  • , Brian T. Anderson
  • , William Brennan
  • , Rebecka Bremler
  • , Joost J. Breeksema
  • , Lisa Burback
  • , Abigail E. Calder
  • , Robin L. Carhart-Harris
  • , Katherine Cheung
  • , Neşe Devenot
  • , Ingmar Gorman
  • , Jakub Greń
  • , Peter S. Hendricks
  • , Brian Holoyda
  • , Edward Jacobs
  • , Joy Krecké
  • , Daniel J. Kruger
  • , David Luke
  • , Tomislav Majić
  • Amy L. McGuire, Nicky J. Mehtani, David S. Mathai, Kristin Nash, Tehseen Noorani, Roman Palitsky, Oliver C. Robinson, Otto Simonsson, Elin Stahre, Michiel van Elk, David B. Yaden
  • The Challenging Psychedelic Experiences Project
  • International Center for Ethnobotanical Education, Research and Service (ICEERS)
  • University of California at San Francisco
  • University of California at Berkeley
  • GuideSite Consulting LLC
  • Imperial College London
  • University of Groningen
  • University of Alberta
  • University of Fribourg
  • Johns Hopkins University
  • Fluence
  • Institute of Psychiatry and Neurology, Warszawa
  • University of Alabama at Birmingham
  • Medical College of Wisconsin
  • Contra Costa County Detention Health Services
  • University of Oxford
  • University of Exeter
  • University of Greenwich
  • Charité – Universitätsmedizin Berlin
  • Baylor College of Medicine
  • William G. Nash Foundation Santa Monica California
  • The University of Auckland
  • Emory University
  • Karolinska Institutet
  • Leiden University

Research output: Contribution to journalComment/debate

11 Scopus citations

Abstract

Objective: This article outlines recommendations from 30 psychedelic researchers on how to create a better psychedelic safety net. Methods: A survey of 30 psychedelic researchers asked them to identify key critical research gaps around psychedelic harm and safety. Results: The critical research gaps identified by the authors included defining the main types of psychedelic harm, the predictors of those harms, and the most effective way to treat those harms. They also call for better support for those experiencing post-psychedelic difficulties, including better online information, peer support groups, affordable therapy, and psychiatric consultation and medication. Finally, the authors call for better funding to create a psychedelic safety net, and suggest psychedelic philanthropists, investors and companies could commit 1% of their investment in psychedelics into supporting safety measures such as research and support services. Conclusions: The authors identify several practical steps to create a better psychedelic safety net and call for more funding to psychedelic safety measures such as research and support services. Relevance to clinical practice: The authors outline important gaps in our knowledge around the safety and risk profile of psychedelic medicines and identify practical steps forward for researchers and clinical practitioners to make this promising field safer.

Original languageEnglish
Pages (from-to)4-8
Number of pages5
JournalPsychiatric Research and Clinical Practice
Volume7
Issue number1
DOIs
StatePublished - Mar 1 2025

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