TY - JOUR
T1 - Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence
AU - Allergic Rhinitis and Its Impact on Asthma Working Group
AU - Bousquet, Jean
AU - Schünemann, Holger J.
AU - Togias, Akdis
AU - Bachert, Claus
AU - Erhola, Martina
AU - Hellings, Peter W.
AU - Klimek, Ludger
AU - Pfaar, Oliver
AU - Wallace, Dana
AU - Ansotegui, Ignacio
AU - Agache, Ioana
AU - Bedbrook, Anna
AU - Bergmann, Karl Christian
AU - Bewick, Mike
AU - Bonniaud, Philippe
AU - Bosnic-Anticevich, Sinthia
AU - Bossé, Isabelle
AU - Bouchard, Jacques
AU - Boulet, Louis Philippe
AU - Brozek, Jan
AU - Brusselle, Guy
AU - Calderon, Moises A.
AU - Canonica, Walter G.
AU - Caraballo, Luis
AU - Cardona, Vicky
AU - Casale, Thomas
AU - Cecchi, Lorenzo
AU - Chu, Derek K.
AU - Costa, Elisio M.
AU - Cruz, Alvaro A.
AU - Czarlewski, Wienczyslawa
AU - D'Amato, Gennaro
AU - Devillier, Philippe
AU - Dykewicz, Mark
AU - Ebisawa, Motohiro
AU - Fauquert, Jean Louis
AU - Fokkens, Wytske J.
AU - Fonseca, Joao A.
AU - Fontaine, Jean François
AU - Gemicioglu, Bilun
AU - van Wijk, Roy Gerth
AU - Haahtela, Tari
AU - Halken, Susanne
AU - Ierodiakonou, Despo
AU - Iinuma, Tomohisa
AU - Ivancevich, Juan Carlos
AU - Jutel, Marek
AU - Kaidashev, Igor
AU - Khaitov, Musa
AU - Kalayci, Omer
N1 - Publisher Copyright:
© 2019 American Academy of Allergy, Asthma & Immunology
PY - 2020/1
Y1 - 2020/1
N2 - The selection of pharmacotherapy for patients with allergic rhinitis aims to control the disease and depends on many factors. Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines have considerably improved the treatment of allergic rhinitis. However, there is an increasing trend toward use of real-world evidence to inform clinical practice, especially because randomized controlled trials are often limited with regard to the applicability of results. The Contre les Maladies Chroniques pour un Vieillissement Actif (MACVIA) algorithm has proposed an allergic rhinitis treatment by a consensus group. This simple algorithm can be used to step up or step down allergic rhinitis treatment. Next-generation guidelines for the pharmacologic treatment of allergic rhinitis were developed by using existing GRADE-based guidelines for the disease, real-world evidence provided by mobile technology, and additive studies (allergen chamber studies) to refine the MACVIA algorithm.
AB - The selection of pharmacotherapy for patients with allergic rhinitis aims to control the disease and depends on many factors. Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines have considerably improved the treatment of allergic rhinitis. However, there is an increasing trend toward use of real-world evidence to inform clinical practice, especially because randomized controlled trials are often limited with regard to the applicability of results. The Contre les Maladies Chroniques pour un Vieillissement Actif (MACVIA) algorithm has proposed an allergic rhinitis treatment by a consensus group. This simple algorithm can be used to step up or step down allergic rhinitis treatment. Next-generation guidelines for the pharmacologic treatment of allergic rhinitis were developed by using existing GRADE-based guidelines for the disease, real-world evidence provided by mobile technology, and additive studies (allergen chamber studies) to refine the MACVIA algorithm.
KW - Allergic Rhinitis and Its Impact on Asthma
KW - Allergic rhinitis
KW - Development and Evaluation
KW - Grading of Recommendations Assessment
KW - guidelines
KW - real-world evidence
UR - https://www.scopus.com/pages/publications/85073509724
U2 - 10.1016/j.jaci.2019.06.049
DO - 10.1016/j.jaci.2019.06.049
M3 - Review article
C2 - 31627910
AN - SCOPUS:85073509724
SN - 0091-6749
VL - 145
SP - 70-80.e3
JO - Journal of Allergy and Clinical Immunology
JF - Journal of Allergy and Clinical Immunology
IS - 1
ER -