New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions

Andrew T. Kuhls; Vikas Patel; Ciprian Ionita; Peter B. Noël; Alan M. Walczak; Hussain S. Rangwala; Kenneth R. Hoffmann; Stephen Rudin

doi:10.1117/12.653654

New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions

Andrew T. Kuhls
, Vikas Patel
, Ciprian Ionita
, Peter B. Noël
, Alan M. Walczak
, Hussain S. Rangwala
, Kenneth R. Hoffmann
, Stephen Rudin

SUNY Buffalo

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

6 Scopus citations

Abstract

A new microangiographic system (MA) integrated into a c-arm gantry has been developed allowing precise placement of a MA at the exact same angle as the standard x-ray image intensifier (II) with unchanged source and object position. The MA can also be arbitrarily moved about the object and easily moved into the field of view (FOV) in front of the lower resolution II when higher resolution angiographic sequences are needed. The benefits of this new system are illustrated in a neurovascular study, where a rabbit is injected with contrast media for varying oblique angles. Digital subtraction angiographic (DSA) images were obtained and compared using both the MA and II detectors for the same projection view. Vessels imaged with the MA appear sharper with smaller vessels visualized. Visualization of ∼100 μm vessels was possible with the MA whereas not with the II. Further, the MA could better resolve vessel overlap. Contrast to noise ratios (CNR) were calculated for vessels of varying sizes for the MA versus the II and were found to be similar for large vessels, approximately double for medium vessels, and infinitely better for the smallest vessels. In addition, a 3D reconstruction of selected vessel segments was performed, using multiple (three) projections at oblique angles, for each detector. This new MA/II integrated system should lead to improved diagnosis and image guidance of neurovascular interventions by enabling initial guidance with the low resolution large FOV II combined with use of the high resolution MA during critical parts of diagnostic and interventional procedures.

Original language	English
Title of host publication	Medical Imaging 2006
Subtitle of host publication	Physics of Medical Imaging
DOIs	https://doi.org/10.1117/12.653654
State	Published - 2006
Event	Medical Imaging 2006: Physics of Medical Imaging - San Diego, CA, United States Duration: Feb 12 2006 → Feb 16 2006

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	6142 III
ISSN (Print)	1605-7422

Conference

Conference	Medical Imaging 2006: Physics of Medical Imaging
Country/Territory	United States
City	San Diego, CA
Period	02/12/06 → 02/16/06

Keywords

Detector technology
Digital angiography
Image guided interventions
Image intensifier
Image reconstructions
Microangiography
Multiview
X-ray detectors
X-ray tomosynthesis

Access to Document

10.1117/12.653654

Cite this

Kuhls, A. T., Patel, V., Ionita, C., Noël, P. B., Walczak, A. M., Rangwala, H. S., Hoffmann, K. R., & Rudin, S. (2006). New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions. In Medical Imaging 2006: Physics of Medical Imaging Article 61423M (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6142 III). https://doi.org/10.1117/12.653654

@inproceedings{c0ec4493030f49f4ad92ac05c7f1b2ac,

title = "New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions",

abstract = "A new microangiographic system (MA) integrated into a c-arm gantry has been developed allowing precise placement of a MA at the exact same angle as the standard x-ray image intensifier (II) with unchanged source and object position. The MA can also be arbitrarily moved about the object and easily moved into the field of view (FOV) in front of the lower resolution II when higher resolution angiographic sequences are needed. The benefits of this new system are illustrated in a neurovascular study, where a rabbit is injected with contrast media for varying oblique angles. Digital subtraction angiographic (DSA) images were obtained and compared using both the MA and II detectors for the same projection view. Vessels imaged with the MA appear sharper with smaller vessels visualized. Visualization of ∼100 μm vessels was possible with the MA whereas not with the II. Further, the MA could better resolve vessel overlap. Contrast to noise ratios (CNR) were calculated for vessels of varying sizes for the MA versus the II and were found to be similar for large vessels, approximately double for medium vessels, and infinitely better for the smallest vessels. In addition, a 3D reconstruction of selected vessel segments was performed, using multiple (three) projections at oblique angles, for each detector. This new MA/II integrated system should lead to improved diagnosis and image guidance of neurovascular interventions by enabling initial guidance with the low resolution large FOV II combined with use of the high resolution MA during critical parts of diagnostic and interventional procedures.",

keywords = "Detector technology, Digital angiography, Image guided interventions, Image intensifier, Image reconstructions, Microangiography, Multiview, X-ray detectors, X-ray tomosynthesis",

author = "Kuhls, \{Andrew T.\} and Vikas Patel and Ciprian Ionita and No{\"e}l, \{Peter B.\} and Walczak, \{Alan M.\} and Rangwala, \{Hussain S.\} and Hoffmann, \{Kenneth R.\} and Stephen Rudin",

year = "2006",

doi = "10.1117/12.653654",

language = "English",

isbn = "0819461857",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

booktitle = "Medical Imaging 2006",

note = "Medical Imaging 2006: Physics of Medical Imaging ; Conference date: 12-02-2006 Through 16-02-2006",

}

Kuhls, AT, Patel, V, Ionita, C, Noël, PB, Walczak, AM, Rangwala, HS, Hoffmann, KR & Rudin, S 2006, New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions. in Medical Imaging 2006: Physics of Medical Imaging., 61423M, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 6142 III, Medical Imaging 2006: Physics of Medical Imaging, San Diego, CA, United States, 02/12/06. https://doi.org/10.1117/12.653654

New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions. / Kuhls, Andrew T.; Patel, Vikas; Ionita, Ciprian et al.
Medical Imaging 2006: Physics of Medical Imaging. 2006. 61423M (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6142 III).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions

AU - Kuhls, Andrew T.

AU - Patel, Vikas

AU - Ionita, Ciprian

AU - Noël, Peter B.

AU - Walczak, Alan M.

AU - Rangwala, Hussain S.

AU - Hoffmann, Kenneth R.

AU - Rudin, Stephen

PY - 2006

Y1 - 2006

N2 - A new microangiographic system (MA) integrated into a c-arm gantry has been developed allowing precise placement of a MA at the exact same angle as the standard x-ray image intensifier (II) with unchanged source and object position. The MA can also be arbitrarily moved about the object and easily moved into the field of view (FOV) in front of the lower resolution II when higher resolution angiographic sequences are needed. The benefits of this new system are illustrated in a neurovascular study, where a rabbit is injected with contrast media for varying oblique angles. Digital subtraction angiographic (DSA) images were obtained and compared using both the MA and II detectors for the same projection view. Vessels imaged with the MA appear sharper with smaller vessels visualized. Visualization of ∼100 μm vessels was possible with the MA whereas not with the II. Further, the MA could better resolve vessel overlap. Contrast to noise ratios (CNR) were calculated for vessels of varying sizes for the MA versus the II and were found to be similar for large vessels, approximately double for medium vessels, and infinitely better for the smallest vessels. In addition, a 3D reconstruction of selected vessel segments was performed, using multiple (three) projections at oblique angles, for each detector. This new MA/II integrated system should lead to improved diagnosis and image guidance of neurovascular interventions by enabling initial guidance with the low resolution large FOV II combined with use of the high resolution MA during critical parts of diagnostic and interventional procedures.

AB - A new microangiographic system (MA) integrated into a c-arm gantry has been developed allowing precise placement of a MA at the exact same angle as the standard x-ray image intensifier (II) with unchanged source and object position. The MA can also be arbitrarily moved about the object and easily moved into the field of view (FOV) in front of the lower resolution II when higher resolution angiographic sequences are needed. The benefits of this new system are illustrated in a neurovascular study, where a rabbit is injected with contrast media for varying oblique angles. Digital subtraction angiographic (DSA) images were obtained and compared using both the MA and II detectors for the same projection view. Vessels imaged with the MA appear sharper with smaller vessels visualized. Visualization of ∼100 μm vessels was possible with the MA whereas not with the II. Further, the MA could better resolve vessel overlap. Contrast to noise ratios (CNR) were calculated for vessels of varying sizes for the MA versus the II and were found to be similar for large vessels, approximately double for medium vessels, and infinitely better for the smallest vessels. In addition, a 3D reconstruction of selected vessel segments was performed, using multiple (three) projections at oblique angles, for each detector. This new MA/II integrated system should lead to improved diagnosis and image guidance of neurovascular interventions by enabling initial guidance with the low resolution large FOV II combined with use of the high resolution MA during critical parts of diagnostic and interventional procedures.

KW - Detector technology

KW - Digital angiography

KW - Image guided interventions

KW - Image intensifier

KW - Image reconstructions

KW - Microangiography

KW - Multiview

KW - X-ray detectors

KW - X-ray tomosynthesis

UR - https://www.scopus.com/pages/publications/33745159587

U2 - 10.1117/12.653654

DO - 10.1117/12.653654

M3 - Conference contribution

AN - SCOPUS:33745159587

SN - 0819461857

SN - 9780819461858

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Medical Imaging 2006

T2 - Medical Imaging 2006: Physics of Medical Imaging

Y2 - 12 February 2006 through 16 February 2006

ER -

Kuhls AT, Patel V, Ionita C, Noël PB, Walczak AM, Rangwala HS et al. New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions. In Medical Imaging 2006: Physics of Medical Imaging. 2006. 61423M. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.653654

New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions

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