New light-amplifier-based detector designs for high spatial resolution and high sensitivity CBCT mammography and fluoroscopy

Stephen Rudin; Andrew T. Kuhls; Girijesh K. Yadava; Gaurav C. Josan; Ye Wu; Ravishankar N. Chityala; Hussain S. Rangwala; N. Ciprian Ionita; Kenneth R. Hoffmann; Daniel R. Bednarek

doi:10.1117/12.649501

New light-amplifier-based detector designs for high spatial resolution and high sensitivity CBCT mammography and fluoroscopy

Stephen Rudin
, Andrew T. Kuhls
, Girijesh K. Yadava
, Gaurav C. Josan
, Ye Wu
, Ravishankar N. Chityala
, Hussain S. Rangwala
, N. Ciprian Ionita
, Kenneth R. Hoffmann
, Daniel R. Bednarek

SUNY Buffalo

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

22 Scopus citations

Abstract

New cone-beam computed tomographic (CBCT) mammography system designs are presented where the detectors provide high spatial resolution, high sensitivity, low noise, wide dynamic range, negligible lag and high frame rates similar to features required for high performance fluoroscopy detectors. The x-ray detectors consist of a phosphor coupled by a fiber-optic taper to either a high gain image light amplifier (LA) then CCD camera or to an electron multiplying CCD. When a square-array of such detectors is used, a field-of-view (FOV) to 20 × 20 cm can be obtained where the images have pixel-resolution of 100 urn or better. To achieve practical CBCT mammography scan-times, 30 fps may be acquired with quantum limited (noise free) performance below 0.2 μR detector exposure per frame. Because of the flexible voltage controlled gain of the LA's and EMCCDs, large detector dynamic range is also achievable. Features of such detector systems with arrays of either generation 2 (Gen 2) or 3 (Gen 3) LAs optically coupled to CCD cameras or arrays of EMCCDs coupled directly are compared. Quantum accounting analysis is done for a variety of such designs where either the lowest number of information carriers off the LA photo-cathode or electrons released in the EMCCDs per x-ray absorbed in the phosphor are large enough to imply no quantum sink for the design. These new LA- or EMCCD-based systems could lead to vastly improved CBCT mammography, ROI-CT, or fluoroscopy performance compared to systems using flat panels.

Original language	English
Title of host publication	Medical Imaging 2006
Subtitle of host publication	Physics of Medical Imaging
DOIs	https://doi.org/10.1117/12.649501
State	Published - 2006
Event	Medical Imaging 2006: Physics of Medical Imaging - San Diego, CA, United States Duration: Feb 12 2006 → Feb 16 2006

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	6142 II
ISSN (Print)	1605-7422

Conference

Conference	Medical Imaging 2006: Physics of Medical Imaging
Country/Territory	United States
City	San Diego, CA
Period	02/12/06 → 02/16/06

Keywords

CT
Cone beam computed tomography
Detector arrays
Detector mosaic
Electron multiplying CCD
Fluoroscopy
Light amplifiers
Mammography
Quantum accounting
X-ray detectors

Access to Document

10.1117/12.649501

Cite this

Rudin, S., Kuhls, A. T., Yadava, G. K., Josan, G. C., Wu, Y., Chityala, R. N., Rangwala, H. S., Ionita, N. C., Hoffmann, K. R., & Bednarek, D. R. (2006). New light-amplifier-based detector designs for high spatial resolution and high sensitivity CBCT mammography and fluoroscopy. In Medical Imaging 2006: Physics of Medical Imaging Article 61421R (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6142 II). https://doi.org/10.1117/12.649501

@inproceedings{397131168baa4771bd439bba0d614cd2,

title = "New light-amplifier-based detector designs for high spatial resolution and high sensitivity CBCT mammography and fluoroscopy",

abstract = "New cone-beam computed tomographic (CBCT) mammography system designs are presented where the detectors provide high spatial resolution, high sensitivity, low noise, wide dynamic range, negligible lag and high frame rates similar to features required for high performance fluoroscopy detectors. The x-ray detectors consist of a phosphor coupled by a fiber-optic taper to either a high gain image light amplifier (LA) then CCD camera or to an electron multiplying CCD. When a square-array of such detectors is used, a field-of-view (FOV) to 20 × 20 cm can be obtained where the images have pixel-resolution of 100 urn or better. To achieve practical CBCT mammography scan-times, 30 fps may be acquired with quantum limited (noise free) performance below 0.2 μR detector exposure per frame. Because of the flexible voltage controlled gain of the LA's and EMCCDs, large detector dynamic range is also achievable. Features of such detector systems with arrays of either generation 2 (Gen 2) or 3 (Gen 3) LAs optically coupled to CCD cameras or arrays of EMCCDs coupled directly are compared. Quantum accounting analysis is done for a variety of such designs where either the lowest number of information carriers off the LA photo-cathode or electrons released in the EMCCDs per x-ray absorbed in the phosphor are large enough to imply no quantum sink for the design. These new LA- or EMCCD-based systems could lead to vastly improved CBCT mammography, ROI-CT, or fluoroscopy performance compared to systems using flat panels.",

keywords = "CT, Cone beam computed tomography, Detector arrays, Detector mosaic, Electron multiplying CCD, Fluoroscopy, Light amplifiers, Mammography, Quantum accounting, X-ray detectors",

author = "Stephen Rudin and Kuhls, \{Andrew T.\} and Yadava, \{Girijesh K.\} and Josan, \{Gaurav C.\} and Ye Wu and Chityala, \{Ravishankar N.\} and Rangwala, \{Hussain S.\} and Ionita, \{N. Ciprian\} and Hoffmann, \{Kenneth R.\} and Bednarek, \{Daniel R.\}",

year = "2006",

doi = "10.1117/12.649501",

language = "English",

isbn = "0819461857",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

booktitle = "Medical Imaging 2006",

note = "Medical Imaging 2006: Physics of Medical Imaging ; Conference date: 12-02-2006 Through 16-02-2006",

}

Rudin, S, Kuhls, AT, Yadava, GK, Josan, GC, Wu, Y, Chityala, RN, Rangwala, HS, Ionita, NC , Hoffmann, KR & Bednarek, DR 2006, New light-amplifier-based detector designs for high spatial resolution and high sensitivity CBCT mammography and fluoroscopy. in Medical Imaging 2006: Physics of Medical Imaging., 61421R, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 6142 II, Medical Imaging 2006: Physics of Medical Imaging, San Diego, CA, United States, 02/12/06. https://doi.org/10.1117/12.649501

New light-amplifier-based detector designs for high spatial resolution and high sensitivity CBCT mammography and fluoroscopy. / Rudin, Stephen; Kuhls, Andrew T.; Yadava, Girijesh K. et al.
Medical Imaging 2006: Physics of Medical Imaging. 2006. 61421R (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6142 II).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - New light-amplifier-based detector designs for high spatial resolution and high sensitivity CBCT mammography and fluoroscopy

AU - Rudin, Stephen

AU - Kuhls, Andrew T.

AU - Yadava, Girijesh K.

AU - Josan, Gaurav C.

AU - Wu, Ye

AU - Chityala, Ravishankar N.

AU - Rangwala, Hussain S.

AU - Ionita, N. Ciprian

AU - Hoffmann, Kenneth R.

AU - Bednarek, Daniel R.

PY - 2006

Y1 - 2006

N2 - New cone-beam computed tomographic (CBCT) mammography system designs are presented where the detectors provide high spatial resolution, high sensitivity, low noise, wide dynamic range, negligible lag and high frame rates similar to features required for high performance fluoroscopy detectors. The x-ray detectors consist of a phosphor coupled by a fiber-optic taper to either a high gain image light amplifier (LA) then CCD camera or to an electron multiplying CCD. When a square-array of such detectors is used, a field-of-view (FOV) to 20 × 20 cm can be obtained where the images have pixel-resolution of 100 urn or better. To achieve practical CBCT mammography scan-times, 30 fps may be acquired with quantum limited (noise free) performance below 0.2 μR detector exposure per frame. Because of the flexible voltage controlled gain of the LA's and EMCCDs, large detector dynamic range is also achievable. Features of such detector systems with arrays of either generation 2 (Gen 2) or 3 (Gen 3) LAs optically coupled to CCD cameras or arrays of EMCCDs coupled directly are compared. Quantum accounting analysis is done for a variety of such designs where either the lowest number of information carriers off the LA photo-cathode or electrons released in the EMCCDs per x-ray absorbed in the phosphor are large enough to imply no quantum sink for the design. These new LA- or EMCCD-based systems could lead to vastly improved CBCT mammography, ROI-CT, or fluoroscopy performance compared to systems using flat panels.

AB - New cone-beam computed tomographic (CBCT) mammography system designs are presented where the detectors provide high spatial resolution, high sensitivity, low noise, wide dynamic range, negligible lag and high frame rates similar to features required for high performance fluoroscopy detectors. The x-ray detectors consist of a phosphor coupled by a fiber-optic taper to either a high gain image light amplifier (LA) then CCD camera or to an electron multiplying CCD. When a square-array of such detectors is used, a field-of-view (FOV) to 20 × 20 cm can be obtained where the images have pixel-resolution of 100 urn or better. To achieve practical CBCT mammography scan-times, 30 fps may be acquired with quantum limited (noise free) performance below 0.2 μR detector exposure per frame. Because of the flexible voltage controlled gain of the LA's and EMCCDs, large detector dynamic range is also achievable. Features of such detector systems with arrays of either generation 2 (Gen 2) or 3 (Gen 3) LAs optically coupled to CCD cameras or arrays of EMCCDs coupled directly are compared. Quantum accounting analysis is done for a variety of such designs where either the lowest number of information carriers off the LA photo-cathode or electrons released in the EMCCDs per x-ray absorbed in the phosphor are large enough to imply no quantum sink for the design. These new LA- or EMCCD-based systems could lead to vastly improved CBCT mammography, ROI-CT, or fluoroscopy performance compared to systems using flat panels.

KW - CT

KW - Cone beam computed tomography

KW - Detector arrays

KW - Detector mosaic

KW - Electron multiplying CCD

KW - Fluoroscopy

KW - Light amplifiers

KW - Mammography

KW - Quantum accounting

KW - X-ray detectors

UR - https://www.scopus.com/pages/publications/33745347356

U2 - 10.1117/12.649501

DO - 10.1117/12.649501

M3 - Conference contribution

AN - SCOPUS:33745347356

SN - 0819461857

SN - 9780819461858

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Medical Imaging 2006

T2 - Medical Imaging 2006: Physics of Medical Imaging

Y2 - 12 February 2006 through 16 February 2006

ER -

New light-amplifier-based detector designs for high spatial resolution and high sensitivity CBCT mammography and fluoroscopy

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Keywords

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