Neonatal Thyroid Function and Disorders

Alison K. Chapman; Zachary J. Farmer; Lucy D. Mastrandrea; Kristal A. Matlock

doi:10.1097/GRF.0000000000000434

Neonatal Thyroid Function and Disorders

Alison K. Chapman
, Zachary J. Farmer
, Lucy D. Mastrandrea
, Kristal A. Matlock

Pediatrics

Divisions of Neonatology
Medical University of South Carolina

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Thyroid hormone is essential for normal fetal brain development in utero and for the first 2 years of life. The developing fetus is initially reliant upon maternal thyroid hormones that cross the placenta, until the fetal thyroid begins to supply thyroid hormone for the fetus. Maternal thyroid status affects fetal thyroid function and maternal thyroid dysfunction can have a significant impact on the fetus and neonate. There are also several neonatal factors that can influence thyroid function. Here, we describe thyroid function in the fetus and neonate and discuss the most common thyroid disorders seen in neonates.

Original language	English
Pages (from-to)	373-387
Number of pages	15
Journal	Clinical Obstetrics and Gynecology
Volume	62
Issue number	2
DOIs	https://doi.org/10.1097/GRF.0000000000000434
State	Published - Jun 1 2019

Keywords

congenital hypothyroidism
hypothyroxinemia
neonatal Graves disease
neonatal hyperthyroidism
transient hypothyroidism

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10.1097/GRF.0000000000000434

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title = "Neonatal Thyroid Function and Disorders",

abstract = "Thyroid hormone is essential for normal fetal brain development in utero and for the first 2 years of life. The developing fetus is initially reliant upon maternal thyroid hormones that cross the placenta, until the fetal thyroid begins to supply thyroid hormone for the fetus. Maternal thyroid status affects fetal thyroid function and maternal thyroid dysfunction can have a significant impact on the fetus and neonate. There are also several neonatal factors that can influence thyroid function. Here, we describe thyroid function in the fetus and neonate and discuss the most common thyroid disorders seen in neonates.",

keywords = "congenital hypothyroidism, hypothyroxinemia, neonatal Graves disease, neonatal hyperthyroidism, transient hypothyroidism",

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doi = "10.1097/GRF.0000000000000434",

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T1 - Neonatal Thyroid Function and Disorders

AU - Chapman, Alison K.

AU - Farmer, Zachary J.

AU - Mastrandrea, Lucy D.

AU - Matlock, Kristal A.

PY - 2019/6/1

Y1 - 2019/6/1

N2 - Thyroid hormone is essential for normal fetal brain development in utero and for the first 2 years of life. The developing fetus is initially reliant upon maternal thyroid hormones that cross the placenta, until the fetal thyroid begins to supply thyroid hormone for the fetus. Maternal thyroid status affects fetal thyroid function and maternal thyroid dysfunction can have a significant impact on the fetus and neonate. There are also several neonatal factors that can influence thyroid function. Here, we describe thyroid function in the fetus and neonate and discuss the most common thyroid disorders seen in neonates.

AB - Thyroid hormone is essential for normal fetal brain development in utero and for the first 2 years of life. The developing fetus is initially reliant upon maternal thyroid hormones that cross the placenta, until the fetal thyroid begins to supply thyroid hormone for the fetus. Maternal thyroid status affects fetal thyroid function and maternal thyroid dysfunction can have a significant impact on the fetus and neonate. There are also several neonatal factors that can influence thyroid function. Here, we describe thyroid function in the fetus and neonate and discuss the most common thyroid disorders seen in neonates.

KW - congenital hypothyroidism

KW - hypothyroxinemia

KW - neonatal Graves disease

KW - neonatal hyperthyroidism

KW - transient hypothyroidism

UR - https://www.scopus.com/pages/publications/85064914989

U2 - 10.1097/GRF.0000000000000434

DO - 10.1097/GRF.0000000000000434

M3 - Article

C2 - 31026231

AN - SCOPUS:85064914989

SN - 0009-9201

VL - 62

SP - 373

EP - 387

JO - Clinical Obstetrics and Gynecology

JF - Clinical Obstetrics and Gynecology

IS - 2

ER -

Neonatal Thyroid Function and Disorders

Abstract

Keywords

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