Na+ channel function, regulation, structure, trafficking and sequestration

Ye Chen-Izu; Robin M. Shaw; Geoffrey S. Pitt; Vladimir Yarov-Yarovoy; Jon T. Sack; Hugues Abriel; Richard W. Aldrich; Luiz Belardinelli; Mark B. Cannell; William A. Catterall; Walter J. Chazin; Nipavan Chiamvimonvat; Isabelle Deschenes; Eleonora Grandi; Thomas J. Hund; Leighton T. Izu; Lars S. Maier; Victor A. Maltsev; Celine Marionneau; Peter J. Mohler; Sridharan Rajamani; Randall L. Rasmusson; Eric A. Sobie; Colleen E. Clancy; Donald M. Bers

doi:10.1113/jphysiol.2014.281428

Na⁺ channel function, regulation, structure, trafficking and sequestration

Ye Chen-Izu
, Robin M. Shaw
, Geoffrey S. Pitt
, Vladimir Yarov-Yarovoy
, Jon T. Sack
, Hugues Abriel
, Richard W. Aldrich
, Luiz Belardinelli
, Mark B. Cannell
, William A. Catterall
, Walter J. Chazin
, Nipavan Chiamvimonvat
, Isabelle Deschenes
, Eleonora Grandi
, Thomas J. Hund
, Leighton T. Izu
, Lars S. Maier
, Victor A. Maltsev
, Celine Marionneau
, Peter J. Mohler

Sridharan Rajamani, Randall L. Rasmusson, Eric A. Sobie, Colleen E. Clancy, Donald M. Bers

Physiology and Biophysics

University of California at Davis
Cedars-Sinai Medical Center
Duke University
University of Bern
University of Texas at Austin
Gilead Sciences
University of Bristol
University of Washington
Vanderbilt University
Case Western Reserve University
Ohio State University
University of Regensburg
National Institutes of Health
Nantes Université
Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Article › peer-review

65 Scopus citations

Abstract

This paper is the second of a series of three reviews published in this issue resulting from the University of California Davis Cardiovascular Symposium 2014: Systems approach to understanding cardiac excitation-contraction coupling and arrhythmias: Na⁺ channel and Na⁺ transport. The goal of the symposium was to bring together experts in the field to discuss points of consensus and controversy on the topic of sodium in the heart. The present review focuses on Na⁺ channel function and regulation, Na⁺ channel structure and function, and Na⁺ channel trafficking, sequestration and complexing.

Original language	English
Pages (from-to)	1347-1360
Number of pages	14
Journal	Journal of Physiology
Volume	593
Issue number	6
DOIs	https://doi.org/10.1113/jphysiol.2014.281428
State	Published - Mar 15 2015

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Chen-Izu, Y., Shaw, R. M., Pitt, G. S., Yarov-Yarovoy, V., Sack, J. T., Abriel, H., Aldrich, R. W., Belardinelli, L., Cannell, M. B., Catterall, W. A., Chazin, W. J., Chiamvimonvat, N., Deschenes, I., Grandi, E., Hund, T. J., Izu, L. T., Maier, L. S., Maltsev, V. A., Marionneau, C., ... Bers, D. M. (2015). Na⁺ channel function, regulation, structure, trafficking and sequestration. Journal of Physiology, 593(6), 1347-1360. https://doi.org/10.1113/jphysiol.2014.281428

@article{89dd2325d05140998f240ef3f3381af1,

title = "Na+ channel function, regulation, structure, trafficking and sequestration",

abstract = "This paper is the second of a series of three reviews published in this issue resulting from the University of California Davis Cardiovascular Symposium 2014: Systems approach to understanding cardiac excitation-contraction coupling and arrhythmias: Na+ channel and Na+ transport. The goal of the symposium was to bring together experts in the field to discuss points of consensus and controversy on the topic of sodium in the heart. The present review focuses on Na+ channel function and regulation, Na+ channel structure and function, and Na+ channel trafficking, sequestration and complexing.",

author = "Ye Chen-Izu and Shaw, \{Robin M.\} and Pitt, \{Geoffrey S.\} and Vladimir Yarov-Yarovoy and Sack, \{Jon T.\} and Hugues Abriel and Aldrich, \{Richard W.\} and Luiz Belardinelli and Cannell, \{Mark B.\} and Catterall, \{William A.\} and Chazin, \{Walter J.\} and Nipavan Chiamvimonvat and Isabelle Deschenes and Eleonora Grandi and Hund, \{Thomas J.\} and Izu, \{Leighton T.\} and Maier, \{Lars S.\} and Maltsev, \{Victor A.\} and Celine Marionneau and Mohler, \{Peter J.\} and Sridharan Rajamani and Rasmusson, \{Randall L.\} and Sobie, \{Eric A.\} and Clancy, \{Colleen E.\} and Bers, \{Donald M.\}",

note = "Publisher Copyright: {\textcopyright} 2014 The Physiological Society.",

year = "2015",

month = mar,

day = "15",

doi = "10.1113/jphysiol.2014.281428",

language = "English",

volume = "593",

pages = "1347--1360",

journal = "Journal of Physiology",

issn = "0022-3751",

publisher = "John Wiley and Sons Inc",

number = "6",

}

Chen-Izu, Y, Shaw, RM, Pitt, GS, Yarov-Yarovoy, V, Sack, JT, Abriel, H, Aldrich, RW, Belardinelli, L, Cannell, MB, Catterall, WA, Chazin, WJ, Chiamvimonvat, N, Deschenes, I, Grandi, E, Hund, TJ, Izu, LT, Maier, LS, Maltsev, VA, Marionneau, C, Mohler, PJ, Rajamani, S, Rasmusson, RL, Sobie, EA, Clancy, CE & Bers, DM 2015, 'Na⁺ channel function, regulation, structure, trafficking and sequestration', Journal of Physiology, vol. 593, no. 6, pp. 1347-1360. https://doi.org/10.1113/jphysiol.2014.281428

TY - JOUR

T1 - Na+ channel function, regulation, structure, trafficking and sequestration

AU - Chen-Izu, Ye

AU - Shaw, Robin M.

AU - Pitt, Geoffrey S.

AU - Yarov-Yarovoy, Vladimir

AU - Sack, Jon T.

AU - Abriel, Hugues

AU - Aldrich, Richard W.

AU - Belardinelli, Luiz

AU - Cannell, Mark B.

AU - Catterall, William A.

AU - Chazin, Walter J.

AU - Chiamvimonvat, Nipavan

AU - Deschenes, Isabelle

AU - Grandi, Eleonora

AU - Hund, Thomas J.

AU - Izu, Leighton T.

AU - Maier, Lars S.

AU - Maltsev, Victor A.

AU - Marionneau, Celine

AU - Mohler, Peter J.

AU - Rajamani, Sridharan

AU - Rasmusson, Randall L.

AU - Sobie, Eric A.

AU - Clancy, Colleen E.

AU - Bers, Donald M.

PY - 2015/3/15

Y1 - 2015/3/15

N2 - This paper is the second of a series of three reviews published in this issue resulting from the University of California Davis Cardiovascular Symposium 2014: Systems approach to understanding cardiac excitation-contraction coupling and arrhythmias: Na+ channel and Na+ transport. The goal of the symposium was to bring together experts in the field to discuss points of consensus and controversy on the topic of sodium in the heart. The present review focuses on Na+ channel function and regulation, Na+ channel structure and function, and Na+ channel trafficking, sequestration and complexing.

AB - This paper is the second of a series of three reviews published in this issue resulting from the University of California Davis Cardiovascular Symposium 2014: Systems approach to understanding cardiac excitation-contraction coupling and arrhythmias: Na+ channel and Na+ transport. The goal of the symposium was to bring together experts in the field to discuss points of consensus and controversy on the topic of sodium in the heart. The present review focuses on Na+ channel function and regulation, Na+ channel structure and function, and Na+ channel trafficking, sequestration and complexing.

UR - https://www.scopus.com/pages/publications/84924529893

U2 - 10.1113/jphysiol.2014.281428

DO - 10.1113/jphysiol.2014.281428

M3 - Article

C2 - 25772290

AN - SCOPUS:84924529893

SN - 0022-3751

VL - 593

SP - 1347

EP - 1360

JO - Journal of Physiology

JF - Journal of Physiology

IS - 6

ER -

Na⁺ channel function, regulation, structure, trafficking and sequestration

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