@inbook{002d01fe5b954f09bfb7d0ef7183be7a,
title = "Nanoparticle preparation for magnetothermal genetic stimulation in cell culture and in the brain of live rodents",
abstract = "Remote deep brain activation of specific neurons to evoke functional behavior in unrestrained subjects allows studies of how brain circuitry controls behavior. The local heating of superparamagnetic nanoparticles in alternating magnetic fields can be coupled to temperature sensitive ion channels to modulate neuronal activity in cell culture and in the behaving, awake animal. Application of synthesized ferrite nanoparticles requires pacification of their surface to achieve biocompatibility. In addition, it is often necessary to target the particles to a specific cell region or protein, which requires further conjugation with ligands or antibodies. This chapter discusses the advantages of various nanoparticle surface coating strategies.",
keywords = "Magnetic hyperthermia, Magnetogenetics, Superparamagnetic nanoparticles, Surface pacification, Targeting of nanoparticles",
author = "Idoia Castellanos-Rubio and Rahul Munshi and Shahnaz Qadri and Arnd Pralle",
note = "Publisher Copyright: {\textcopyright} 2018, Springer Science+Business Media LLC.",
year = "2018",
doi = "10.1007/978-1-4939-7584-6\_4",
language = "English",
series = "Neuromethods",
publisher = "Humana Press Inc.",
pages = "39--51",
booktitle = "Neuromethods",
}