N-Chloramine Derivatization Mechanism with Dansyisulfinic Acid: Yields and Routes of Reaction

At present, direct methods for analysis of chloramines are unavailable. Several approaches using derivatization-based methods for their anlaysis have been reported in the literature. One such method employs reaction of chloramines with dansyisulfinic acid to produce stable dansylsulfonamide products, which are analyzed by HPLC. This paper reports results of experiments examining the routes and yields produced during the dansylation of model chloramine solutions. Potential limitations of the method arise due to matrix effects, low yields for dilute chloramine concentrations, and a marked dependence of yield upon the composition of the chloramine pool. These limitations disallow quantitative application of the dansylation method to the analysis of chloramine mixtures.