mSphere of Influence: Adenosine in host defense against bacterial pneumonia-friend or foe?

Elsa N. Bou Ghanem

doi:10.1128/mSphere.00326-19

mSphere of Influence: Adenosine in host defense against bacterial pneumonia-friend or foe?

Elsa N. Bou Ghanem

Microbiology and Immunology

Research output: Contribution to journal › Comment/debate

3 Scopus citations

Abstract

Elsa N. Bou Ghanem works in the field of innate immune senescence, inflammation, and host defense. In this mSphere of Influence article, she reflects on how "Adenosine A_2B receptor deficiency promotes host defenses against Gramnegative bacterial pneumonia" by Barletta et al. (K. E. Barletta, R. E. Cagnina, M. D. Burdick, J. Linden, and B. Mehrad, Am J Respir Crit Care Med 186:1044 -1050, 2012, https://doi.org/10.1164/rccm.201204-0622OC) impacted her own work examining the role of the extracellular adenosine pathway in neutrophil responses and host defense against pneumococcal pneumonia.

Original language	English
Article number	e00326-19
Journal	mSphere
Volume	4
Issue number	4
DOIs	https://doi.org/10.1128/mSphere.00326-19
State	Published - 2019

Keywords

Bacterial pneumonia
CD73
Extracellular adenosine
Inflammation
Lung infection
Neutrophils
Streptococcus pneumoniae

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10.1128/mSphere.00326-19

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@article{b907dcbcfda64742b244e41494faaaf4,

title = "mSphere of Influence: Adenosine in host defense against bacterial pneumonia-friend or foe?",

abstract = "Elsa N. Bou Ghanem works in the field of innate immune senescence, inflammation, and host defense. In this mSphere of Influence article, she reflects on how {"}Adenosine A2B receptor deficiency promotes host defenses against Gramnegative bacterial pneumonia{"} by Barletta et al. (K. E. Barletta, R. E. Cagnina, M. D. Burdick, J. Linden, and B. Mehrad, Am J Respir Crit Care Med 186:1044 -1050, 2012, https://doi.org/10.1164/rccm.201204-0622OC) impacted her own work examining the role of the extracellular adenosine pathway in neutrophil responses and host defense against pneumococcal pneumonia.",

keywords = "Bacterial pneumonia, CD73, Extracellular adenosine, Inflammation, Lung infection, Neutrophils, Streptococcus pneumoniae",

author = "\{Bou Ghanem\}, \{Elsa N.\}",

note = "Publisher Copyright: {\textcopyright} 2019 Bou Ghanem.",

year = "2019",

doi = "10.1128/mSphere.00326-19",

language = "English",

volume = "4",

journal = "mSphere",

issn = "2379-5042",

publisher = "American Society for Microbiology",

number = "4",

}

TY - JOUR

T1 - mSphere of Influence

T2 - Adenosine in host defense against bacterial pneumonia-friend or foe?

AU - Bou Ghanem, Elsa N.

PY - 2019

Y1 - 2019

N2 - Elsa N. Bou Ghanem works in the field of innate immune senescence, inflammation, and host defense. In this mSphere of Influence article, she reflects on how "Adenosine A2B receptor deficiency promotes host defenses against Gramnegative bacterial pneumonia" by Barletta et al. (K. E. Barletta, R. E. Cagnina, M. D. Burdick, J. Linden, and B. Mehrad, Am J Respir Crit Care Med 186:1044 -1050, 2012, https://doi.org/10.1164/rccm.201204-0622OC) impacted her own work examining the role of the extracellular adenosine pathway in neutrophil responses and host defense against pneumococcal pneumonia.

AB - Elsa N. Bou Ghanem works in the field of innate immune senescence, inflammation, and host defense. In this mSphere of Influence article, she reflects on how "Adenosine A2B receptor deficiency promotes host defenses against Gramnegative bacterial pneumonia" by Barletta et al. (K. E. Barletta, R. E. Cagnina, M. D. Burdick, J. Linden, and B. Mehrad, Am J Respir Crit Care Med 186:1044 -1050, 2012, https://doi.org/10.1164/rccm.201204-0622OC) impacted her own work examining the role of the extracellular adenosine pathway in neutrophil responses and host defense against pneumococcal pneumonia.

KW - Bacterial pneumonia

KW - CD73

KW - Extracellular adenosine

KW - Inflammation

KW - Lung infection

KW - Neutrophils

KW - Streptococcus pneumoniae

UR - https://www.scopus.com/pages/publications/85069553692

U2 - 10.1128/mSphere.00326-19

DO - 10.1128/mSphere.00326-19

M3 - Comment/debate

C2 - 31292232

AN - SCOPUS:85069553692

SN - 2379-5042

VL - 4

JO - mSphere

JF - mSphere

IS - 4

M1 - e00326-19

ER -

mSphere of Influence: Adenosine in host defense against bacterial pneumonia-friend or foe?

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