TY - GEN
T1 - Motion tracking and intensity surface recovery in microscopic nuclear images
AU - Mukherjee, Lopamudra
AU - Lin, Mingen
AU - Xu, Jinhui
AU - Berezney, Ronald
PY - 2005
Y1 - 2005
N2 - Current techniques for microscopic imaging do not provide necessary spatial and temporai resolutions for real time visualization of the nucleus. Images can only be acquired in time lapse mode, leading to significant loss of information between image frames. Such data, if available, can be extremely helpful in the study of nuclear organization and function. In this paper, we present a gamut of geometric-technique-based approaches for solving the problem. Our techniques, working together, can effectively recover complicated motion and deformation as well as the change of intensity surfaces from pairs of images in a microscopic image sequence, and has low time complexity, particularly desirable by many biological applications where large amount of DNA need to be processed. These techniques are also readily applicable to other types of images for reconstructing motion and intensity surfaces of deformable objects.
AB - Current techniques for microscopic imaging do not provide necessary spatial and temporai resolutions for real time visualization of the nucleus. Images can only be acquired in time lapse mode, leading to significant loss of information between image frames. Such data, if available, can be extremely helpful in the study of nuclear organization and function. In this paper, we present a gamut of geometric-technique-based approaches for solving the problem. Our techniques, working together, can effectively recover complicated motion and deformation as well as the change of intensity surfaces from pairs of images in a microscopic image sequence, and has low time complexity, particularly desirable by many biological applications where large amount of DNA need to be processed. These techniques are also readily applicable to other types of images for reconstructing motion and intensity surfaces of deformable objects.
UR - https://www.scopus.com/pages/publications/33744806392
U2 - 10.1007/11566465_108
DO - 10.1007/11566465_108
M3 - Conference contribution
C2 - 16685929
AN - SCOPUS:33744806392
SN - 3540293272
SN - 9783540293279
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 876
EP - 884
BT - Medical Image Computing and Computer-Assisted Intervention - MICCAI 2005 - 8th International Conference, Proceedings
T2 - 8th International Conference on Medical Image Computing and Computer-Assisted Intervention - MICCAI 2005
Y2 - 26 October 2005 through 29 October 2005
ER -