TY - GEN
T1 - Monte Carlo simulation of Temperature Distribution for Skin Tissue During Photobiomodulation
AU - Yang, Weibing
AU - Sourvanos, Dennis
AU - Dimofte, Andreea
AU - Busch, Theresa M.
AU - Arany, Praveen
AU - Schoenbaum, Todd
AU - Fiorellini, Joseph P.
AU - Zhu, Timothy C.
N1 - Publisher Copyright:
© 2025 SPIE.
PY - 2025
Y1 - 2025
N2 - Photobiomodulation (PBM) is a non-invasive therapeutic technique that uses low-level laser to stimulate cellular function and promote healing. By delivering light at specific wavelengths, PBM interacts with cellular components to enhance tissue repair, reduce inflammation, and modulate pain. Temperature distribution during PBM treatment is a crucial factor in optimizing treatment protocols. The optical properties of the tissue, such as scattering and absorption, directly influence how heat is generated and distributed, impacting the effectiveness of PBM therapy. This study utilizes Monte Carlo (MC) simulations to model temperature distribution within simulated skin tissue during PBM treatment. By employing MC simulations in MATLAB, we investigate how variations in the tissue's scattering and absorption coefficients for epidermis, dermis and blood vessels impact the resulting temperature distribution. Understanding these thermal effects is crucial for optimizing PBM treatments. The tissue model is designed to simulate the complex interactions between light and biological tissue, capturing how light scattering and absorption affect heat generation and propagation. Temperature distribution within the simplified skin tissue is simulated under various conditions to evaluate the influence of different optical properties. The results of this simulation provide valuable insights into how adjustments to the PBM parameters can optimize therapeutic outcomes, ensuring effective treatment while minimizing the risk of thermal damage. This work aims to contribute to the refinement of PBM treatment protocols by offering a deeper understanding of the thermal dynamics in response to varying tissue optical properties. The findings could guide the development of more precise and personalized PBM therapies.
AB - Photobiomodulation (PBM) is a non-invasive therapeutic technique that uses low-level laser to stimulate cellular function and promote healing. By delivering light at specific wavelengths, PBM interacts with cellular components to enhance tissue repair, reduce inflammation, and modulate pain. Temperature distribution during PBM treatment is a crucial factor in optimizing treatment protocols. The optical properties of the tissue, such as scattering and absorption, directly influence how heat is generated and distributed, impacting the effectiveness of PBM therapy. This study utilizes Monte Carlo (MC) simulations to model temperature distribution within simulated skin tissue during PBM treatment. By employing MC simulations in MATLAB, we investigate how variations in the tissue's scattering and absorption coefficients for epidermis, dermis and blood vessels impact the resulting temperature distribution. Understanding these thermal effects is crucial for optimizing PBM treatments. The tissue model is designed to simulate the complex interactions between light and biological tissue, capturing how light scattering and absorption affect heat generation and propagation. Temperature distribution within the simplified skin tissue is simulated under various conditions to evaluate the influence of different optical properties. The results of this simulation provide valuable insights into how adjustments to the PBM parameters can optimize therapeutic outcomes, ensuring effective treatment while minimizing the risk of thermal damage. This work aims to contribute to the refinement of PBM treatment protocols by offering a deeper understanding of the thermal dynamics in response to varying tissue optical properties. The findings could guide the development of more precise and personalized PBM therapies.
KW - Photobiomodulation (PBM)
KW - monte carlo simulation
KW - skin tissue
KW - temperature distribution
KW - tissue optical properties
UR - https://www.scopus.com/pages/publications/105004291391
U2 - 10.1117/12.3048014
DO - 10.1117/12.3048014
M3 - Conference contribution
AN - SCOPUS:105004291391
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Mechanisms of Photobiomodulation Therapy XIX
A2 - Liebert, Ann
A2 - Lyons, Jeri-Anne
A2 - Carroll, James D.
PB - SPIE
T2 - Mechanisms of Photobiomodulation Therapy XIX 2025
Y2 - 25 January 2025 through 26 January 2025
ER -