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Merkel Cell Carcinoma, Version 1.2024 Featured Updates to the NCCN Guidelines

  • Chrysalyne D. Schmults
  • , Rachel Blitzblau
  • , Sumaira Z. Aasi
  • , Murad Alam
  • , Arya Amini
  • , Kristin Bibee
  • , Diana Bolotin
  • , Jeremy Bordeaux
  • , Pei Ling Chen
  • , Carlo M. Contreras
  • , Dominick DiMaio
  • , Jessica M. Donigan
  • , Jeffrey M. Farma
  • , Karthik Ghosh
  • , Kelly Harms
  • , Alan L. Ho
  • , John Nicholas Lukens
  • , Susan Manber
  • , Lawrence Mark
  • , Theresa Medina
  • Kishwer S. Nehal, Paul Nghiem, Kelly Olino, Soo Park, Tejesh Patel, Igor Puzanov, Jason Rich, Aleksandar Sekulic, Ashok R. Shaha, Divya Srivastava, Valencia Thomas, Courtney Tomblinson, Puja Venkat, Yaohui Gloria Xu, Siegrid Yu, Mehran Yusuf, Beth McCullough, Sara Espinosa
  • Dana-Farber/Brigham and Women's Cancer Center
  • Duke University
  • Stanford University
  • Northwestern University
  • City of Hope National Med Center
  • Johns Hopkins University
  • The University of Chicago
  • Case Western Reserve University
  • Moffitt Cancer Center
  • Ohio State University
  • University of Nebraska Medical Center
  • University of Utah
  • Fox Chase Cancer Center
  • Mayo Clinic Rochester, MN
  • University of Michigan, Ann Arbor
  • Memorial Sloan-Kettering Cancer Center
  • University of Pennsylvania
  • Publicis Health
  • Indiana University Bloomington
  • University of Colorado Anschutz Medical Campus
  • Fred Hutchinson Cancer Research Center
  • Yale University
  • University of California at San Diego
  • University of Tennessee Health Science Center
  • University of Washington
  • UT Southwestern Simmons Comprehensive Cancer Center
  • University of Texas MD Anderson Cancer Center
  • Vanderbilt University
  • University of California at Los Angeles
  • University of Wisconsin-Madison
  • University of California at San Francisco
  • University of Alabama at Birmingham
  • National Comprehensive Cancer Network

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

The NCCN Guidelines for Merkel Cell Carcinoma (MCC) provide recommendations for diagnostic workup, clinical stage, and treatment options for patients. The panel meets annually to discuss updates to the guidelines based on comments fromexpert review frompanelmembers, institutional review, as well as submissions from within NCCN and external organizations. TheseNCCNGuidelines Insights focus on the introduction of a new page for locally advanced disease in the setting of clinical node negative status, entitled "Clinical N0 Disease, Locally Advanced MCC."This new algorithmpage addresses locally advanced disease, and the panel clarifies the meaning behind the term "nonsurgical"by further defining locally advanced disease. In addition, the guideline includes the management of in-transit disease and updates to the systemic therapy options.

Original languageEnglish
Article numbere240002
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume22
Issue number1
DOIs
StatePublished - Jan 2024

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