Leonurenones A-C: Labdane diterpenes from Leonotis leonurus

Fang He; Charlotte Lindqvist; Wayne W. Harding

doi:10.1016/j.phytochem.2012.07.014

Leonurenones A-C: Labdane diterpenes from Leonotis leonurus

Fang He
, Charlotte Lindqvist
, Wayne W. Harding

Biological Sciences

City University of New York

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Labdanes, leonurenones A-C, two known labdanes, luteolin 7-O-β-glucoside and luteolin were isolated and characterized from a commercial source of Leonotis leonurus. Genetic methods allowed for identification of the plant material. The leonurenones contain an uncommon α,β-unsaturated enone moiety in ring B, and leonurenones A and B were evaluated in a competitive inhibition assay at the GABA A neuroreceptor site.

Original language	English
Pages (from-to)	168-172
Number of pages	5
Journal	Phytochemistry
Volume	83
DOIs	https://doi.org/10.1016/j.phytochem.2012.07.014
State	Published - Nov 2012

Keywords

Diterpene
Labdane
Leonotis leonurus
Leonurenone

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10.1016/j.phytochem.2012.07.014

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title = "Leonurenones A-C: Labdane diterpenes from Leonotis leonurus",

abstract = "Labdanes, leonurenones A-C, two known labdanes, luteolin 7-O-β-glucoside and luteolin were isolated and characterized from a commercial source of Leonotis leonurus. Genetic methods allowed for identification of the plant material. The leonurenones contain an uncommon α,β-unsaturated enone moiety in ring B, and leonurenones A and B were evaluated in a competitive inhibition assay at the GABA A neuroreceptor site.",

keywords = "Diterpene, Labdane, Leonotis leonurus, Leonurenone",

author = "Fang He and Charlotte Lindqvist and Harding, \{Wayne W.\}",

year = "2012",

month = nov,

doi = "10.1016/j.phytochem.2012.07.014",

language = "English",

volume = "83",

pages = "168--172",

journal = "Phytochemistry",

issn = "0031-9422",

publisher = "Elsevier Ltd",

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TY - JOUR

T1 - Leonurenones A-C

T2 - Labdane diterpenes from Leonotis leonurus

AU - He, Fang

AU - Lindqvist, Charlotte

AU - Harding, Wayne W.

PY - 2012/11

Y1 - 2012/11

N2 - Labdanes, leonurenones A-C, two known labdanes, luteolin 7-O-β-glucoside and luteolin were isolated and characterized from a commercial source of Leonotis leonurus. Genetic methods allowed for identification of the plant material. The leonurenones contain an uncommon α,β-unsaturated enone moiety in ring B, and leonurenones A and B were evaluated in a competitive inhibition assay at the GABA A neuroreceptor site.

AB - Labdanes, leonurenones A-C, two known labdanes, luteolin 7-O-β-glucoside and luteolin were isolated and characterized from a commercial source of Leonotis leonurus. Genetic methods allowed for identification of the plant material. The leonurenones contain an uncommon α,β-unsaturated enone moiety in ring B, and leonurenones A and B were evaluated in a competitive inhibition assay at the GABA A neuroreceptor site.

KW - Diterpene

KW - Labdane

KW - Leonotis leonurus

KW - Leonurenone

UR - https://www.scopus.com/pages/publications/84867045058

U2 - 10.1016/j.phytochem.2012.07.014

DO - 10.1016/j.phytochem.2012.07.014

M3 - Article

C2 - 22892215

AN - SCOPUS:84867045058

SN - 0031-9422

VL - 83

SP - 168

EP - 172

JO - Phytochemistry

JF - Phytochemistry

ER -

Leonurenones A-C: Labdane diterpenes from Leonotis leonurus

Abstract

Keywords

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