@inproceedings{8bfba51bb90a48c3932f5345b93f82c1,
title = "LED-based portable light source for photodynamic therapy",
abstract = "Photodynamic therapy (PDT) employs light activation of tissue-localized photosensitizer in an oxygen-dependent process which initiates oxidative stress, inflammation, and cell death. Laser systems, which are mostly used in PDT as light sources can be costly and oversized. light-emitting diodes (LEDs) equipment has a high potential to simplify technical part of phototriggered therapies and to reduce its costs. We develop the LED-based system that includes the control and irradiation units. The system provides the same power density at any irradiation point. Among the advantages of the device is a possibility to change the irradiation area and tune the irradiation dose. PDT experiments with cancer cells in vitro treated with two different photosensitizers demonstrated a possibility to use the developed LED-based system as a low-cost light source in PDT.",
keywords = "high power single chip led, light source, photodynamic therapy",
author = "O. Chepurna and A. Grebinyk and Yu Petrushko and S. Prylutska and S. Grebinyk and Yashchuk, \{V. M.\} and O. Matyshevska and U. Ritter and T. Dandekar and M. Frohme and J. Qu and Ohulchanskyy, \{T. Y.\}",
note = "Publisher Copyright: {\textcopyright} 2019 SPIE.; Optics in Health Care and Biomedical Optics IX 2019 ; Conference date: 21-10-2019 Through 23-10-2019",
year = "2019",
doi = "10.1117/12.2541774",
language = "English",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
editor = "Qingming Luo and Qingming Luo and Xingde Li and Ying Gu and Yuguo Tang and Dan Zhu",
booktitle = "Optics in Health Care and Biomedical Optics IX",
address = "United States",
}