Issues involved in using sol-gel-derived glasses as platforms for chemical sensing

Meagan A. Doody; Gary A. Baker; Siddharth Pandey; Neil J. Bonzagni; Frank V. Bright

Issues involved in using sol-gel-derived glasses as platforms for chemical sensing

Meagan A. Doody
, Gary A. Baker
, Siddharth Pandey
, Neil J. Bonzagni
, Frank V. Bright

Chemistry

SUNY Buffalo

Research output: Contribution to journal › Conference article › peer-review

Abstract

Over the past several years our group has been exploring the potential of sol-gel-derived glasses (xerogels) as platforms for advanced sensors and biosensors. In this paper we will outline the challenges that are associated with using these xerogels. Toward this end, we discuss recent results from our laboratories on the performance of polyclonal anti-dansyl antibodies sequestered within a series of xerogels. We assess antibody performance by determining the hapten/antibody association constant, the static excitation and emission for the dansyl hapten bound to the antibody combining site, and the excited-state fluorescence anisotropy and intensity decay kinetics for the dansyl/anti-dansyl system within a series of xerogels.

Original language	English
Pages (from-to)	2-10
Number of pages	9
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	3856
State	Published - 1999
Event	Proceedings of the 1999 Internal Standardization and Calibration Architectures for Chemical Sensors - Boston, MA, USA Duration: Sep 20 1999 → Sep 22 1999

Cite this

@article{36a4cc9dee2d4b9face728cbd78ba71e,

title = "Issues involved in using sol-gel-derived glasses as platforms for chemical sensing",

abstract = "Over the past several years our group has been exploring the potential of sol-gel-derived glasses (xerogels) as platforms for advanced sensors and biosensors. In this paper we will outline the challenges that are associated with using these xerogels. Toward this end, we discuss recent results from our laboratories on the performance of polyclonal anti-dansyl antibodies sequestered within a series of xerogels. We assess antibody performance by determining the hapten/antibody association constant, the static excitation and emission for the dansyl hapten bound to the antibody combining site, and the excited-state fluorescence anisotropy and intensity decay kinetics for the dansyl/anti-dansyl system within a series of xerogels.",

author = "Doody, \{Meagan A.\} and Baker, \{Gary A.\} and Siddharth Pandey and Bonzagni, \{Neil J.\} and Bright, \{Frank V.\}",

year = "1999",

language = "English",

volume = "3856",

pages = "2--10",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

publisher = "SPIE",

note = "Proceedings of the 1999 Internal Standardization and Calibration Architectures for Chemical Sensors ; Conference date: 20-09-1999 Through 22-09-1999",

}

TY - JOUR

T1 - Issues involved in using sol-gel-derived glasses as platforms for chemical sensing

AU - Doody, Meagan A.

AU - Baker, Gary A.

AU - Pandey, Siddharth

AU - Bonzagni, Neil J.

AU - Bright, Frank V.

PY - 1999

Y1 - 1999

N2 - Over the past several years our group has been exploring the potential of sol-gel-derived glasses (xerogels) as platforms for advanced sensors and biosensors. In this paper we will outline the challenges that are associated with using these xerogels. Toward this end, we discuss recent results from our laboratories on the performance of polyclonal anti-dansyl antibodies sequestered within a series of xerogels. We assess antibody performance by determining the hapten/antibody association constant, the static excitation and emission for the dansyl hapten bound to the antibody combining site, and the excited-state fluorescence anisotropy and intensity decay kinetics for the dansyl/anti-dansyl system within a series of xerogels.

AB - Over the past several years our group has been exploring the potential of sol-gel-derived glasses (xerogels) as platforms for advanced sensors and biosensors. In this paper we will outline the challenges that are associated with using these xerogels. Toward this end, we discuss recent results from our laboratories on the performance of polyclonal anti-dansyl antibodies sequestered within a series of xerogels. We assess antibody performance by determining the hapten/antibody association constant, the static excitation and emission for the dansyl hapten bound to the antibody combining site, and the excited-state fluorescence anisotropy and intensity decay kinetics for the dansyl/anti-dansyl system within a series of xerogels.

UR - https://www.scopus.com/pages/publications/0033338294

M3 - Conference article

AN - SCOPUS:0033338294

SN - 0277-786X

VL - 3856

SP - 2

EP - 10

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Proceedings of the 1999 Internal Standardization and Calibration Architectures for Chemical Sensors

Y2 - 20 September 1999 through 22 September 1999

ER -

Issues involved in using sol-gel-derived glasses as platforms for chemical sensing

Abstract

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