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Isolation of a low molecular weight glycoprotein inhibitor of calcium phosphate precipitation from the extra-parotid saliva of macaque monkeys

  • T. E. VanDyke
  • , M. J. Levine
  • , M. C. Herzberg
  • , S. A. Ellison
  • , D. I. Hay
  • SUNY Buffalo
  • The Forsyth Institute

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

A low molecular weight (9600) glycoprotein was isolated from monkey (Macaca arctoides) extra-parotid saliva by gel filtration on Sephadex G-200 and Sephadex G-50. Criteria of purity included immunodiffusion, immunoelectrophoresis and polyacrylamide gel electrophoresis. The molecule contained 76 per cent protein, 23.4 per cent carbohydrate and 0.6 per cent phosphorus. The glycoprotein was a potent inhibitor of calcium phosphate precipitation.

Original languageEnglish
Pages (from-to)85-89
Number of pages5
JournalArchives of Oral Biology
Volume24
Issue number2
DOIs
StatePublished - 1979

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