Is there a preferred diuretic class for patients with renal impairment and hypertension?

Joseph L. Izzo; Sheldon W. Tobe

doi:10.1016/j.jash.2016.02.008

Is there a preferred diuretic class for patients with renal impairment and hypertension?

Joseph L. Izzo
, Sheldon W. Tobe

Medicine

SUNY Buffalo
University of Toronto

Research output: Contribution to journal › Comment/debate

5 Scopus citations

Abstract

It is widely believed that "high-ceiling" loop diuretics are required in patients with renal impairment and that "low-ceiling" thiazides are not sufficiently potent to cause meaningful natriuresis and diuresis. If this statement is true, at what level of renal function do thiazides lose their punch? Another related issue is the enlightened use of diuretic combinations. Use of diuretics in chronic kidney disease and hypertension has been addressed in the many guidelines, but further insight is provided in this installment of the "Controversies" series by two well-known authorities, William Elliott, M.D. Ph.D. and Rajiv Agarwal, M.D.

Original language	English
Pages (from-to)	282-284
Number of pages	3
Journal	Journal of the American Society of Hypertension
Volume	10
Issue number	4
DOIs	https://doi.org/10.1016/j.jash.2016.02.008
State	Published - Apr 1 2016

Keywords

Chronic kidney disease
hypertension
loop diuretics
thiazide diuretics

Access to Document

10.1016/j.jash.2016.02.008

Cite this

@article{bf06b4dbbd1c4b68bfb40154c0ff7b3d,

title = "Is there a preferred diuretic class for patients with renal impairment and hypertension?",

abstract = "It is widely believed that {"}high-ceiling{"} loop diuretics are required in patients with renal impairment and that {"}low-ceiling{"} thiazides are not sufficiently potent to cause meaningful natriuresis and diuresis. If this statement is true, at what level of renal function do thiazides lose their punch? Another related issue is the enlightened use of diuretic combinations. Use of diuretics in chronic kidney disease and hypertension has been addressed in the many guidelines, but further insight is provided in this installment of the {"}Controversies{"} series by two well-known authorities, William Elliott, M.D. Ph.D. and Rajiv Agarwal, M.D.",

keywords = "Chronic kidney disease, hypertension, loop diuretics, thiazide diuretics",

author = "Izzo, \{Joseph L.\} and Tobe, \{Sheldon W.\}",

year = "2016",

month = apr,

day = "1",

doi = "10.1016/j.jash.2016.02.008",

language = "English",

volume = "10",

pages = "282--284",

journal = "Journal of the American Society of Hypertension",

issn = "1933-1711",