Introduction

Multiple sclerosis (MS) is recognized as one of the most common reasons for neurological disability in the young and working population. Latest epidemiological studies have estimated that up to 2.7 million people live with MS worldwide, with highest prevalence in the northern parts of the world such as the United States, Canada, and Western Europe. The disability accrued as a result of the disease substantially impacts the quality of life of people with MS with both physical and cognitive impairments contributing to professional and social limitations. Being life-long disease, it also results with a significant societal economic cost. For example, the annual burden of MS in the United States is estimated over US$85 billion. Similar economic and social burden is described around the world.