Interval estimation and hypothesis testing of intraclass correlation coefficients: The generalized variable approach

In this paper, we propose a novel approach using the concept of generalized variable (GV) for the confidence interval estimation of the difference of two intraclass correlation coefficients under unequal family sizes. This approach can also easily provide P-values for hypothesis testing. Simulation results show that the GV approach can provide confidence intervals with good coverage properties and perform hypothesis testing with satisfactory type-I error control. Furthermore, the confidence intervals and P-values by GV approach can be easily obtained by simulation. Therefore the GV approach is a suitable candidate for making inference concerning two intraclass correlation coefficients.