Interaction of recombinant retroviruses with fibronectin yields high efficiencies of gene transfer

Stelios Andreadis; Bharat Bajaj; Pedro Lei

Interaction of recombinant retroviruses with fibronectin yields high efficiencies of gene transfer

Stelios Andreadis
, Bharat Bajaj
, Pedro Lei

Department of Chemical and Biological Engineering

SUNY Buffalo

Research output: Contribution to journal › Conference article › peer-review

Abstract

Studies were performed to exploit the ability of recombinant retroviruses to bind fibronectin and initiate gene transfer by co-localization with target cells. The kinetics of retrovirus-mediated, fibronectin-assisted gene transfer (FAGT) were determined. Further, the conditions that increase the transduction efficiency to levels significantly higher than traditional gene transfer were identified.

Original language	English
Pages (from-to)	S-24
Journal	Annals of Biomedical Engineering
Volume	28
Issue number	SUPPL. 1
State	Published - 2000
Event	2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA Duration: Oct 12 2000 → Oct 14 2000

Cite this

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title = "Interaction of recombinant retroviruses with fibronectin yields high efficiencies of gene transfer",

abstract = "Studies were performed to exploit the ability of recombinant retroviruses to bind fibronectin and initiate gene transfer by co-localization with target cells. The kinetics of retrovirus-mediated, fibronectin-assisted gene transfer (FAGT) were determined. Further, the conditions that increase the transduction efficiency to levels significantly higher than traditional gene transfer were identified.",

author = "Stelios Andreadis and Bharat Bajaj and Pedro Lei",

year = "2000",

language = "English",

volume = "28",

pages = "S--24",

journal = "Annals of Biomedical Engineering",

issn = "0090-6964",

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note = "2000 Annual Fall Meeting of the Biomedical Engineering Society ; Conference date: 12-10-2000 Through 14-10-2000",

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TY - JOUR

T1 - Interaction of recombinant retroviruses with fibronectin yields high efficiencies of gene transfer

AU - Andreadis, Stelios

AU - Bajaj, Bharat

AU - Lei, Pedro

PY - 2000

Y1 - 2000

N2 - Studies were performed to exploit the ability of recombinant retroviruses to bind fibronectin and initiate gene transfer by co-localization with target cells. The kinetics of retrovirus-mediated, fibronectin-assisted gene transfer (FAGT) were determined. Further, the conditions that increase the transduction efficiency to levels significantly higher than traditional gene transfer were identified.

AB - Studies were performed to exploit the ability of recombinant retroviruses to bind fibronectin and initiate gene transfer by co-localization with target cells. The kinetics of retrovirus-mediated, fibronectin-assisted gene transfer (FAGT) were determined. Further, the conditions that increase the transduction efficiency to levels significantly higher than traditional gene transfer were identified.

UR - https://www.scopus.com/pages/publications/0034511379

M3 - Conference article

AN - SCOPUS:0034511379

SN - 0090-6964

VL - 28

SP - S-24

JO - Annals of Biomedical Engineering

JF - Annals of Biomedical Engineering

IS - SUPPL. 1

T2 - 2000 Annual Fall Meeting of the Biomedical Engineering Society

Y2 - 12 October 2000 through 14 October 2000

ER -

Interaction of recombinant retroviruses with fibronectin yields high efficiencies of gene transfer

Abstract

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