Insights into Resistance against Lincosamide Antibiotics

Jesse A. Sundlov; Andrew M. Gulick

doi:10.1016/j.str.2009.11.001

Insights into Resistance against Lincosamide Antibiotics

Jesse A. Sundlov
, Andrew M. Gulick

Department of Structural Biology

SUNY Buffalo

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

Bacteria utilize multiple strategies to circumvent antibiotics, producing broad specificity exporters or enzymes that catalyze the modification of either antibiotics or their targets. A report in this issue of Structure provides the structural and catalytic mechanisms of LinB, an adenylyltransferase of E. faecium that confers resistance to the lincosamide antibiotic clindamycin.

Original language	English
Pages (from-to)	1549-1550
Number of pages	2
Journal	Structure
Volume	17
Issue number	12
DOIs	https://doi.org/10.1016/j.str.2009.11.001
State	Published - Dec 9 2009

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title = "Insights into Resistance against Lincosamide Antibiotics",

abstract = "Bacteria utilize multiple strategies to circumvent antibiotics, producing broad specificity exporters or enzymes that catalyze the modification of either antibiotics or their targets. A report in this issue of Structure provides the structural and catalytic mechanisms of LinB, an adenylyltransferase of E. faecium that confers resistance to the lincosamide antibiotic clindamycin.",

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AU - Sundlov, Jesse A.

AU - Gulick, Andrew M.

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AB - Bacteria utilize multiple strategies to circumvent antibiotics, producing broad specificity exporters or enzymes that catalyze the modification of either antibiotics or their targets. A report in this issue of Structure provides the structural and catalytic mechanisms of LinB, an adenylyltransferase of E. faecium that confers resistance to the lincosamide antibiotic clindamycin.

UR - https://www.scopus.com/pages/publications/71049157114

U2 - 10.1016/j.str.2009.11.001

DO - 10.1016/j.str.2009.11.001

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SN - 0969-2126

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JO - Structure

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Insights into Resistance against Lincosamide Antibiotics

Abstract

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