Initial evaluation of LabPET/SPECT dual modality animal imaging system

Rutao Yao; Xiao Deng; Jean François Beaudoin; Tianyu Ma; Jules Cadorette; Zixiong Cao; Roger Lecomte

doi:10.1109/TNS.2012.2233216

Initial evaluation of LabPET/SPECT dual modality animal imaging system

Rutao Yao
, Xiao Deng
, Jean François Beaudoin
, Tianyu Ma
, Jules Cadorette
, Zixiong Cao
, Roger Lecomte

Radiology

SUNY Buffalo
Rush University Medical Center
Centre Hospitalier Universitaire de Sherbrooke, Centre de Recherche Clinique Étienne-Le Bel
Université de Sherbrooke
Tsinghua University

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

We developed SPECT imaging capability on a LabPET animal scanner to provide an integrated PET/SPECT dual-modality imaging system. The add-on SPECT sub-system was enabled by 1) mechanically integrating a multiple-pinhole collimator in the PET detector ring, and 2) configuring the detectors to acquire singles events in the 120-160 keV range. We report on the design parameters, data acquisition protocols and initial performance assessment of this cost-effective SPECT imaging solution. Phantom and animal images demonstrating the relevance of the system for various imaging tasks in preclinical research are presented.

Original language	English
Article number	6413261
Pages (from-to)	76-81
Number of pages	6
Journal	IEEE Transactions on Nuclear Science
Volume	60
Issue number	1
DOIs	https://doi.org/10.1109/TNS.2012.2233216
State	Published - 2013

Keywords

Animal dual-modality imaging
multiple pinhole collimator
PET/SPECT

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10.1109/TNS.2012.2233216

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title = "Initial evaluation of LabPET/SPECT dual modality animal imaging system",

abstract = "We developed SPECT imaging capability on a LabPET animal scanner to provide an integrated PET/SPECT dual-modality imaging system. The add-on SPECT sub-system was enabled by 1) mechanically integrating a multiple-pinhole collimator in the PET detector ring, and 2) configuring the detectors to acquire singles events in the 120-160 keV range. We report on the design parameters, data acquisition protocols and initial performance assessment of this cost-effective SPECT imaging solution. Phantom and animal images demonstrating the relevance of the system for various imaging tasks in preclinical research are presented.",

keywords = "Animal dual-modality imaging, multiple pinhole collimator, PET/SPECT",

author = "Rutao Yao and Xiao Deng and Beaudoin, \{Jean Fran{\c c}ois\} and Tianyu Ma and Jules Cadorette and Zixiong Cao and Roger Lecomte",

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AU - Yao, Rutao

AU - Deng, Xiao

AU - Beaudoin, Jean François

AU - Ma, Tianyu

AU - Cadorette, Jules

AU - Cao, Zixiong

AU - Lecomte, Roger

PY - 2013

Y1 - 2013

N2 - We developed SPECT imaging capability on a LabPET animal scanner to provide an integrated PET/SPECT dual-modality imaging system. The add-on SPECT sub-system was enabled by 1) mechanically integrating a multiple-pinhole collimator in the PET detector ring, and 2) configuring the detectors to acquire singles events in the 120-160 keV range. We report on the design parameters, data acquisition protocols and initial performance assessment of this cost-effective SPECT imaging solution. Phantom and animal images demonstrating the relevance of the system for various imaging tasks in preclinical research are presented.

AB - We developed SPECT imaging capability on a LabPET animal scanner to provide an integrated PET/SPECT dual-modality imaging system. The add-on SPECT sub-system was enabled by 1) mechanically integrating a multiple-pinhole collimator in the PET detector ring, and 2) configuring the detectors to acquire singles events in the 120-160 keV range. We report on the design parameters, data acquisition protocols and initial performance assessment of this cost-effective SPECT imaging solution. Phantom and animal images demonstrating the relevance of the system for various imaging tasks in preclinical research are presented.

KW - Animal dual-modality imaging

KW - multiple pinhole collimator

KW - PET/SPECT

UR - https://www.scopus.com/pages/publications/84873703544

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JO - IEEE Transactions on Nuclear Science

JF - IEEE Transactions on Nuclear Science

IS - 1

M1 - 6413261

ER -

Initial evaluation of LabPET/SPECT dual modality animal imaging system

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Keywords

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