Inheritance of structural alleles for goat hemoglobins: Site duplication and limited structural divergence for the alpha-chain locus

Michael D. Garrick; James P. Charlton

doi:10.1007/BF00485723

Inheritance of structural alleles for goat hemoglobins: Site duplication and limited structural divergence for the alpha-chain locus

Michael D. Garrick
, James P. Charlton

Biochemistry

University of Virginia

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Four hemoglobin phenotypes have been detected among domestic goats by zonal electrophoresis. Breeding data indicate that two of these phenotypes represent animals homozygous at relevant structural loci and two represent heterozygotes. Electrophoresis of hemoglobin chains reveals both α- and β-chain variation. The phenotypes are interpreted in terms of genotypes which require a postulated duplication and subsequent divergence for the original α-chain structural locus (see Fig. 5).

Original language	English
Pages (from-to)	393-402
Number of pages	10
Journal	Biochemical Genetics
Volume	3
Issue number	4
DOIs	https://doi.org/10.1007/BF00485723
State	Published - Aug 1969

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10.1007/BF00485723

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title = "Inheritance of structural alleles for goat hemoglobins: Site duplication and limited structural divergence for the alpha-chain locus",

abstract = "Four hemoglobin phenotypes have been detected among domestic goats by zonal electrophoresis. Breeding data indicate that two of these phenotypes represent animals homozygous at relevant structural loci and two represent heterozygotes. Electrophoresis of hemoglobin chains reveals both α- and β-chain variation. The phenotypes are interpreted in terms of genotypes which require a postulated duplication and subsequent divergence for the original α-chain structural locus (see Fig. 5).",

author = "Garrick, \{Michael D.\} and Charlton, \{James P.\}",

year = "1969",

month = aug,

doi = "10.1007/BF00485723",

language = "English",

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pages = "393--402",

journal = "Biochemical Genetics",

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T1 - Inheritance of structural alleles for goat hemoglobins

T2 - Site duplication and limited structural divergence for the alpha-chain locus

AU - Garrick, Michael D.

AU - Charlton, James P.

PY - 1969/8

Y1 - 1969/8

N2 - Four hemoglobin phenotypes have been detected among domestic goats by zonal electrophoresis. Breeding data indicate that two of these phenotypes represent animals homozygous at relevant structural loci and two represent heterozygotes. Electrophoresis of hemoglobin chains reveals both α- and β-chain variation. The phenotypes are interpreted in terms of genotypes which require a postulated duplication and subsequent divergence for the original α-chain structural locus (see Fig. 5).

AB - Four hemoglobin phenotypes have been detected among domestic goats by zonal electrophoresis. Breeding data indicate that two of these phenotypes represent animals homozygous at relevant structural loci and two represent heterozygotes. Electrophoresis of hemoglobin chains reveals both α- and β-chain variation. The phenotypes are interpreted in terms of genotypes which require a postulated duplication and subsequent divergence for the original α-chain structural locus (see Fig. 5).

UR - https://www.scopus.com/pages/publications/0014552382

U2 - 10.1007/BF00485723

DO - 10.1007/BF00485723

M3 - Article

C2 - 5365515

AN - SCOPUS:0014552382

SN - 0006-2928

VL - 3

SP - 393

EP - 402

JO - Biochemical Genetics

JF - Biochemical Genetics

IS - 4

ER -

Inheritance of structural alleles for goat hemoglobins: Site duplication and limited structural divergence for the alpha-chain locus

Abstract

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