Abstract
New molecular, cellular, and immunologic techniques used to study host-pathogen interactions have led to a reexamination of the role of infection in chronic obstructive pulmonary disease (COPD). There is now considerable evidence that infection plays a major role in the pathogenesis and clinical course of COPD. A vicious circle of infection and inflammation is thought to lead to exacerbations of the disease.
| Original language | English |
|---|---|
| Pages (from-to) | 2355 |
| Number of pages | 1 |
| Journal | New England Journal of Medicine |
| Volume | 359 |
| Issue number | 22 |
| DOIs | |
| State | Published - Nov 27 2008 |
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