Increased serum pigment epithelium derived factor levels in Type 2 diabetes patients

Alicia Jenkins; Sarah X. Zhang; Albina Gosmanova; Christopher Aston; Azar Dashti; Mary Zoe Baker; Timothy Lyons; Jian Xing Ma

doi:10.1016/j.diabres.2008.06.019

Increased serum pigment epithelium derived factor levels in Type 2 diabetes patients

Alicia Jenkins
, Sarah X. Zhang
, Albina Gosmanova
, Christopher Aston
, Azar Dashti
, Mary Zoe Baker
, Timothy Lyons
, Jian Xing Ma

Department of Ophthalmology

Endocrinology
University of Melbourne
University of Oklahoma
Department of Veterans Affairs

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

Abstract

Serum PEDF levels (mean (S.D.)) were increased in 96 Type 2 diabetic vs. 54 non-diabetic subjects; 5.3 (2.8) vs. 3.2 (2.0) μg/ml, p < 0.001. In diabetes, PEDF correlated with BMI, serum creatinine and LDL-cholesterol, but not with other lipids, HbA1c or CRP. PEDF did not differ by drugs, complications, or gender.

Original language	English
Pages (from-to)	e5-e7
Journal	Diabetes Research and Clinical Practice
Volume	82
Issue number	1
DOIs	https://doi.org/10.1016/j.diabres.2008.06.019
State	Published - Oct 2008

Keywords

Clinical research
Human
Inflammation
Pigment Epithelium Derived Factor
Renal dysfunction
Type 2 diabetes

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10.1016/j.diabres.2008.06.019

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title = "Increased serum pigment epithelium derived factor levels in Type 2 diabetes patients",

abstract = "Serum PEDF levels (mean (S.D.)) were increased in 96 Type 2 diabetic vs. 54 non-diabetic subjects; 5.3 (2.8) vs. 3.2 (2.0) μg/ml, p < 0.001. In diabetes, PEDF correlated with BMI, serum creatinine and LDL-cholesterol, but not with other lipids, HbA1c or CRP. PEDF did not differ by drugs, complications, or gender.",

keywords = "Clinical research, Human, Inflammation, Pigment Epithelium Derived Factor, Renal dysfunction, Type 2 diabetes",

author = "Alicia Jenkins and Zhang, \{Sarah X.\} and Albina Gosmanova and Christopher Aston and Azar Dashti and Baker, \{Mary Zoe\} and Timothy Lyons and Ma, \{Jian Xing\}",

year = "2008",

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doi = "10.1016/j.diabres.2008.06.019",

language = "English",

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T1 - Increased serum pigment epithelium derived factor levels in Type 2 diabetes patients

AU - Jenkins, Alicia

AU - Zhang, Sarah X.

AU - Gosmanova, Albina

AU - Aston, Christopher

AU - Dashti, Azar

AU - Baker, Mary Zoe

AU - Lyons, Timothy

AU - Ma, Jian Xing

PY - 2008/10

Y1 - 2008/10

N2 - Serum PEDF levels (mean (S.D.)) were increased in 96 Type 2 diabetic vs. 54 non-diabetic subjects; 5.3 (2.8) vs. 3.2 (2.0) μg/ml, p < 0.001. In diabetes, PEDF correlated with BMI, serum creatinine and LDL-cholesterol, but not with other lipids, HbA1c or CRP. PEDF did not differ by drugs, complications, or gender.

AB - Serum PEDF levels (mean (S.D.)) were increased in 96 Type 2 diabetic vs. 54 non-diabetic subjects; 5.3 (2.8) vs. 3.2 (2.0) μg/ml, p < 0.001. In diabetes, PEDF correlated with BMI, serum creatinine and LDL-cholesterol, but not with other lipids, HbA1c or CRP. PEDF did not differ by drugs, complications, or gender.

KW - Clinical research

KW - Human

KW - Inflammation

KW - Pigment Epithelium Derived Factor

KW - Renal dysfunction

KW - Type 2 diabetes

UR - https://www.scopus.com/pages/publications/52949093160

U2 - 10.1016/j.diabres.2008.06.019

DO - 10.1016/j.diabres.2008.06.019

M3 - Article

C2 - 18715664

AN - SCOPUS:52949093160

SN - 0168-8227

VL - 82

SP - e5-e7

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

IS - 1

ER -

Increased serum pigment epithelium derived factor levels in Type 2 diabetes patients

Abstract

Keywords

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