Improving foldamer synthesis through protecting group induced unfolding of aromatic oligoamides

Aimin Zhang; Joseph S. Ferguson; Kazuhiro Yamato; Chong Zheng; Bing Gong

doi:10.1021/ol062103d

Improving foldamer synthesis through protecting group induced unfolding of aromatic oligoamides

Aimin Zhang
, Joseph S. Ferguson
, Kazuhiro Yamato
, Chong Zheng
, Bing Gong

Chemistry

SUNY Buffalo
Northern Illinois University

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

(Chemical Equation Presented) The hydrogen bond rigidified backbones of aromatic oligoamides are temporarily interrupted by replacing the amide hydrogens with the acid-labile 2,4-dimethoxybenzyl (DMB) group, which allows the efficient preparation of long folding oligomers that, upon removal of the DMB groups, fold into multiturn helices.

Original language	English
Pages (from-to)	5117-5120
Number of pages	4
Journal	Organic Letters
Volume	8
Issue number	22
DOIs	https://doi.org/10.1021/ol062103d
State	Published - Oct 26 2006

Access to Document

10.1021/ol062103d

Cite this

@article{c94fec4e01854ea7bebef246d64173a9,

title = "Improving foldamer synthesis through protecting group induced unfolding of aromatic oligoamides",

abstract = "(Chemical Equation Presented) The hydrogen bond rigidified backbones of aromatic oligoamides are temporarily interrupted by replacing the amide hydrogens with the acid-labile 2,4-dimethoxybenzyl (DMB) group, which allows the efficient preparation of long folding oligomers that, upon removal of the DMB groups, fold into multiturn helices.",

author = "Aimin Zhang and Ferguson, \{Joseph S.\} and Kazuhiro Yamato and Chong Zheng and Bing Gong",

year = "2006",

month = oct,

day = "26",

doi = "10.1021/ol062103d",

language = "English",

volume = "8",

pages = "5117--5120",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "22",

}

TY - JOUR

T1 - Improving foldamer synthesis through protecting group induced unfolding of aromatic oligoamides

AU - Zhang, Aimin

AU - Ferguson, Joseph S.

AU - Yamato, Kazuhiro

AU - Zheng, Chong

AU - Gong, Bing

PY - 2006/10/26

Y1 - 2006/10/26

N2 - (Chemical Equation Presented) The hydrogen bond rigidified backbones of aromatic oligoamides are temporarily interrupted by replacing the amide hydrogens with the acid-labile 2,4-dimethoxybenzyl (DMB) group, which allows the efficient preparation of long folding oligomers that, upon removal of the DMB groups, fold into multiturn helices.

AB - (Chemical Equation Presented) The hydrogen bond rigidified backbones of aromatic oligoamides are temporarily interrupted by replacing the amide hydrogens with the acid-labile 2,4-dimethoxybenzyl (DMB) group, which allows the efficient preparation of long folding oligomers that, upon removal of the DMB groups, fold into multiturn helices.

UR - https://www.scopus.com/pages/publications/33750904422

U2 - 10.1021/ol062103d

DO - 10.1021/ol062103d

M3 - Article

AN - SCOPUS:33750904422

SN - 1523-7060

VL - 8

SP - 5117

EP - 5120

JO - Organic Letters

JF - Organic Letters

IS - 22

ER -

Improving foldamer synthesis through protecting group induced unfolding of aromatic oligoamides

Abstract

Access to Document

Other files and links

Fingerprint

Cite this