Imaging Entire Genetically Functional Dna Molecules with the Scanning Tunneling Microscope

D. P. Allison; T. Thundat

doi:10.1116/1.578310

Imaging Entire Genetically Functional Dna Molecules with the Scanning Tunneling Microscope

D. P. Allison
, T. Thundat

Department of Chemical and Biological Engineering

Oak Ridge National Laboratory
Georgia Institute of Technology

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Deoxyribonucleic acid (DNA) can be immobilized on epitaxial gold surfaces treated with 2-dimethylarninoethanethiol preventing removal of the molecules due to forces exerted by the scanning tunneling microscope probe tip. We present reproducible images of entire plasmid molecules on these surfaces and discuss differences in image contrast that we have observed.

Original language	English
Pages (from-to)	816-819
Number of pages	4
Journal	Journal of Vacuum Science and Technology A: Vacuum, Surfaces and Films
Volume	11
Issue number	4
DOIs	https://doi.org/10.1116/1.578310
State	Published - Jul 1993

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title = "Imaging Entire Genetically Functional Dna Molecules with the Scanning Tunneling Microscope",

abstract = "Deoxyribonucleic acid (DNA) can be immobilized on epitaxial gold surfaces treated with 2-dimethylarninoethanethiol preventing removal of the molecules due to forces exerted by the scanning tunneling microscope probe tip. We present reproducible images of entire plasmid molecules on these surfaces and discuss differences in image contrast that we have observed.",

author = "Allison, \{D. P.\} and T. Thundat",

year = "1993",

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T1 - Imaging Entire Genetically Functional Dna Molecules with the Scanning Tunneling Microscope

AU - Allison, D. P.

AU - Thundat, T.

PY - 1993/7

Y1 - 1993/7

N2 - Deoxyribonucleic acid (DNA) can be immobilized on epitaxial gold surfaces treated with 2-dimethylarninoethanethiol preventing removal of the molecules due to forces exerted by the scanning tunneling microscope probe tip. We present reproducible images of entire plasmid molecules on these surfaces and discuss differences in image contrast that we have observed.

AB - Deoxyribonucleic acid (DNA) can be immobilized on epitaxial gold surfaces treated with 2-dimethylarninoethanethiol preventing removal of the molecules due to forces exerted by the scanning tunneling microscope probe tip. We present reproducible images of entire plasmid molecules on these surfaces and discuss differences in image contrast that we have observed.

UR - https://www.scopus.com/pages/publications/21144470578

U2 - 10.1116/1.578310

DO - 10.1116/1.578310

M3 - Article

AN - SCOPUS:21144470578

SN - 0734-2101

VL - 11

SP - 816

EP - 819

JO - Journal of Vacuum Science and Technology A: Vacuum, Surfaces and Films

JF - Journal of Vacuum Science and Technology A: Vacuum, Surfaces and Films

IS - 4

ER -

Imaging Entire Genetically Functional Dna Molecules with the Scanning Tunneling Microscope

Abstract

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