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Identifying actionable statements in Chinese health guidelines: a cross-sectional study

  • Xiangying Ren
  • , Tamara Lotfi
  • , Jiyu Chen
  • , Yuling Lei
  • , Chenyibei Zhou
  • , Wei Zhang
  • , Qiao Huang
  • , Yongbo Wang
  • , Siyu Yan
  • , Shichun Wang
  • , Siyuan Ruan
  • , Wanru Wang
  • , Qiyi Zhang
  • , Xiaomei Yao
  • , Yinghui Jin
  • , Holger J. Schuenemann
  • Zhongnan Hospital of Wuhan University
  • McMaster University
  • Wuhan University
  • Hangzhou Normal University
  • Children’s Hospital of Fudan University

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Objective The purpose of this study is to validate the taxonomy and framework using Chinese guidelines and identify actionable statements. Design and setting We searched five databases, to identify the health guidelines from 1 January 2020 to 1 May 2023. Five researchers categorised statements into six types: formal recommendations (Type I) with clear direction and strength, with explicit and direct evidence; good practice statements (GPS) (Type II), actionable in isolation with a significant benefit; remarks (Type III), an inseparable unit belonging to a formal recommendation or GPS that provides additional clarification; research only recommendations (Type IV) for specific populations; implementation considerations, tools and tips (Type V), that describe the how, who, where, what and when, in relation to implementing a recommendation and lacking a direct evidence link; and informal recommendations (Type VI), unrelated to evidence and not meeting GPS criteria. Results We included 116 guidelines, including 74 Western medicine guidelines, 12 traditional Chinese medicine guidelines and 30 integrated Chinese and Western medicine guidelines. 99 guidelines (85.3%) used the Grading of Recommendations Assessment, Development and Evaluation criteria. Medical specialty societies developed the highest number of guidelines (53.4%). Of all the statements, 4422 statements were extracted from the guidelines. Among them, 2154 (48.7%) were formal recommendations, 197 (4.4%) were GPS, 394 (8.9%) were remarks, 16 (0.4%) were research only recommendations, 1106 (25.0%) were implementation considerations, tools and tips, and 555 (12.6%) were informal recommendations. Conclusions Up to date, the Chinese guideline developers tend to overestimate the number of formal recommendations and underestimate the number of GPS, remarks, research only recommendations, implementation considerations, tools and tips, and informal recommendations. Thus the current quality of actionable statements in Chinese health guidelines requires further enhancement.

Original languageEnglish
Pages (from-to)305-312
Number of pages8
JournalBMJ Evidence-Based Medicine
Volume30
Issue number5
DOIs
StatePublished - Oct 1 2025

Keywords

  • Methods

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