Identification of a nuclear protein matrix

Ronald Berezney; Donald S. Coffey

doi:10.1016/0006-291X(74)90355-6

Identification of a nuclear protein matrix

Ronald Berezney
, Donald S. Coffey

Biological Sciences

Johns Hopkins University

Research output: Contribution to journal › Article › peer-review

840 Scopus citations

Abstract

The structural framework of the rat liver nucleus has been identified and consists of a nuclear protein matrix. This matrix is 98.4% protein, 0.1% DNA, 1.2% RNA, and 0.5% phospholipid. The nuclear protein matrix is composed primarily of three acidic polypeptide fractions in the molecular weight range of 60-70,000 daltons.

Original language	English
Pages (from-to)	1410-1417
Number of pages	8
Journal	Biochemical and Biophysical Research Communications
Volume	60
Issue number	4
DOIs	https://doi.org/10.1016/0006-291X(74)90355-6
State	Published - Oct 23 1974

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@article{5375188ae08b4d6b96ca414ffe6331c4,

title = "Identification of a nuclear protein matrix",

abstract = "The structural framework of the rat liver nucleus has been identified and consists of a nuclear protein matrix. This matrix is 98.4\% protein, 0.1\% DNA, 1.2\% RNA, and 0.5\% phospholipid. The nuclear protein matrix is composed primarily of three acidic polypeptide fractions in the molecular weight range of 60-70,000 daltons.",

author = "Ronald Berezney and Coffey, \{Donald S.\}",

year = "1974",

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AU - Berezney, Ronald

AU - Coffey, Donald S.

PY - 1974/10/23

Y1 - 1974/10/23

N2 - The structural framework of the rat liver nucleus has been identified and consists of a nuclear protein matrix. This matrix is 98.4% protein, 0.1% DNA, 1.2% RNA, and 0.5% phospholipid. The nuclear protein matrix is composed primarily of three acidic polypeptide fractions in the molecular weight range of 60-70,000 daltons.

AB - The structural framework of the rat liver nucleus has been identified and consists of a nuclear protein matrix. This matrix is 98.4% protein, 0.1% DNA, 1.2% RNA, and 0.5% phospholipid. The nuclear protein matrix is composed primarily of three acidic polypeptide fractions in the molecular weight range of 60-70,000 daltons.

UR - https://www.scopus.com/pages/publications/0016302398

U2 - 10.1016/0006-291X(74)90355-6

DO - 10.1016/0006-291X(74)90355-6

M3 - Article

C2 - 4214419

AN - SCOPUS:0016302398

SN - 0006-291X

VL - 60

SP - 1410

EP - 1417

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

IS - 4

ER -

Identification of a nuclear protein matrix

Abstract

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