Abstract
Human reproductive tracts represent components of the mucosal immune system with unique features. Although secretory IgA is present, IgG is more abundant, and typical mucosa-associated lymphoid tissue for generating common mucosal immune responses is absent. Antibody responses to genital infections or to locally applied vaccines are usually modest, but alternative strategies for eliciting genital tract antibodies are being developed.
| Original language | English |
|---|---|
| Pages (from-to) | 667-677 |
| Number of pages | 11 |
| Journal | Microbes and Infection |
| Volume | 4 |
| Issue number | 6 |
| DOIs | |
| State | Published - 2002 |
Keywords
- Antibodies
- IgG
- Immune response
- Immunization
- Immunoglobulins
- Mucosal immunity
- Reproductive tract
- Secretory IgA
- Sexually transmitted diseases
- Vaccines
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