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Human submandibular gland statherin and basic histidine-rich peptide are encoded by highly abundant mRNA's derived from a common ancestral sequence

  • SUNY Buffalo

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

The molecular cloning of sequences encoding human submandibular gland (SMG) statherin and a basic histidine-rich peptide is described. The corresponding mRNA's were highly abundant in the human and the Rhesus monkey (Macaca mulatta) SMG, but no homologous message was detectable in the murine SMG. Sequence analysis revealed strong homology between the statherin and basic histidine-rich mRNA's, suggesting their evolution from a common ancestral sequence.

Original languageEnglish
Pages (from-to)784-790
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume149
Issue number2
DOIs
StatePublished - Dec 16 1987

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