Heymann nephritis: Mechanisms of renal injury

D. J. Salant; R. J. Quigg; A. V. Cybulsky

doi:10.1038/ki.1989.81

Heymann nephritis: Mechanisms of renal injury

D. J. Salant
, R. J. Quigg
, A. V. Cybulsky

Medicine

Boston University

Research output: Contribution to journal › Article › peer-review

106 Scopus citations

Abstract

The Heymann nephritis (HN) models of rat membranous nephropathy are extraordinarily valuable tools to investigate the immunopathology of glomerular subepithelial immune deposit formation and the mechanism by which such deposits injure glomeruli. The immunopathology of HN is reviewed by Brentjens and Andres in this volume. In this review we will largely confine ourselves to a discussion of the mediators, mechanisms and pathophysiological consequences of renal injury in rat membranous nephropathy.

Original language	English
Pages (from-to)	976-984
Number of pages	9
Journal	Kidney International
Volume	35
Issue number	4
DOIs	https://doi.org/10.1038/ki.1989.81
State	Published - 1989

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title = "Heymann nephritis: Mechanisms of renal injury",

abstract = "The Heymann nephritis (HN) models of rat membranous nephropathy are extraordinarily valuable tools to investigate the immunopathology of glomerular subepithelial immune deposit formation and the mechanism by which such deposits injure glomeruli. The immunopathology of HN is reviewed by Brentjens and Andres in this volume. In this review we will largely confine ourselves to a discussion of the mediators, mechanisms and pathophysiological consequences of renal injury in rat membranous nephropathy.",

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year = "1989",

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journal = "Kidney International",

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AU - Salant, D. J.

AU - Quigg, R. J.

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N2 - The Heymann nephritis (HN) models of rat membranous nephropathy are extraordinarily valuable tools to investigate the immunopathology of glomerular subepithelial immune deposit formation and the mechanism by which such deposits injure glomeruli. The immunopathology of HN is reviewed by Brentjens and Andres in this volume. In this review we will largely confine ourselves to a discussion of the mediators, mechanisms and pathophysiological consequences of renal injury in rat membranous nephropathy.

AB - The Heymann nephritis (HN) models of rat membranous nephropathy are extraordinarily valuable tools to investigate the immunopathology of glomerular subepithelial immune deposit formation and the mechanism by which such deposits injure glomeruli. The immunopathology of HN is reviewed by Brentjens and Andres in this volume. In this review we will largely confine ourselves to a discussion of the mediators, mechanisms and pathophysiological consequences of renal injury in rat membranous nephropathy.

UR - https://www.scopus.com/pages/publications/0024598866

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DO - 10.1038/ki.1989.81

M3 - Article

C2 - 2651774

AN - SCOPUS:0024598866

SN - 0085-2538

VL - 35

SP - 976

EP - 984

JO - Kidney International

JF - Kidney International

IS - 4

ER -

Heymann nephritis: Mechanisms of renal injury

Abstract

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