TY - GEN
T1 - GPX
T2 - 30th International Conference on Very Large Data Bases, VLDB 2004
AU - Jiang, Daxin
AU - Pei, Jian
AU - Zhang, Aidong
N1 - Publisher Copyright:
© VLDB 2004 - Proceedings of the 30th International Conference on Very Large Data Bases.
PY - 2004
Y1 - 2004
N2 - Discovering co-expressed genes and coherent expression patterns in gene expression data is an important data analysis task in bioinformatics research and biomedical applications. Although various clustering methods have been proposed, two tough challenges still remain on how to integrate the users' domain knowledge and how to handle the high connectivity in the data. Recently, we have systematically studied the problem and proposed an effective approach [3]. In this paper, we describe a demonstration of GPX (for Gene Pattern eXplorer), an integrated environment for interactive exploration of coherent expression patterns and co-expressed genes in gene expression data. GPX integrates several novel techniques, including the coherent pattern index graph, a gene annotation panel, and a graphical interface, to adopt users' domain knowledge and support ex-plorative operations in the clustering procedure. The GPX system as well as its techniques will be showcased, and the progress of GPX will be exemplified using several real-world gene expression data sets.
AB - Discovering co-expressed genes and coherent expression patterns in gene expression data is an important data analysis task in bioinformatics research and biomedical applications. Although various clustering methods have been proposed, two tough challenges still remain on how to integrate the users' domain knowledge and how to handle the high connectivity in the data. Recently, we have systematically studied the problem and proposed an effective approach [3]. In this paper, we describe a demonstration of GPX (for Gene Pattern eXplorer), an integrated environment for interactive exploration of coherent expression patterns and co-expressed genes in gene expression data. GPX integrates several novel techniques, including the coherent pattern index graph, a gene annotation panel, and a graphical interface, to adopt users' domain knowledge and support ex-plorative operations in the clustering procedure. The GPX system as well as its techniques will be showcased, and the progress of GPX will be exemplified using several real-world gene expression data sets.
UR - https://www.scopus.com/pages/publications/105030491952
U2 - 10.1016/b978-012088469-8/50119-4
DO - 10.1016/b978-012088469-8/50119-4
M3 - Conference contribution
AN - SCOPUS:105030491952
T3 - VLDB 2004 - Proceedings of the 30th International Conference on Very Large Data Bases
SP - 1249
EP - 1252
BT - VLDB 2004 - Proceedings of the 30th International Conference on Very Large Data Bases
A2 - Nascimento, Mario A.
A2 - Ozsu, M. Tamer
A2 - Kossmann, Donald
A2 - Miller, Renee J.
A2 - Blakeley, Jose A.
A2 - Schiefer, K. Bernhard
PB - Morgan Kaufmann Publishers, Inc.
Y2 - 31 August 2004 through 3 September 2004
ER -