Abstract
Purpose of review: There is substantial interindividual variation in the response of blood lipids to dietary therapies. The purpose of this review is to highlight recent developments in identifying patient-specific factors that contribute to the significant heterogeneity of responsiveness in lipids to dietary changes and consumption of dietary bioactive compounds. Recent findings: Recent findings suggest that a variety of patient-specific physiological, pathological, environmental, and genetic factors influence the effectiveness of dietary lipid-lowering therapies. Summary: Although genetic markers of responsiveness will revolutionize future personalized nutrition therapies, current research priorities should emphasize the identification of readily accessible metabolic biomarkers of responsiveness in patient subgroups.
| Original language | English |
|---|---|
| Pages (from-to) | 37-42 |
| Number of pages | 6 |
| Journal | Current Opinion in Lipidology |
| Volume | 22 |
| Issue number | 1 |
| DOIs | |
| State | Published - Feb 2011 |
Keywords
- dietary lipid-lowering therapies
- interindividual responsiveness
- nutrigenomics
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