Gene Expression in Bacterial Systems: The trp Operon and Attenuation

P. Gollnick

doi:10.1016/B978-0-12-378630-2.00270-X

Gene Expression in Bacterial Systems: The trp Operon and Attenuation

P. Gollnick

Biological Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Transcription attenuation is defined as any mechanism that utilizes transcriptional pausing or termination to control expression of downstream genes. This mechanism of regulation is used to control expression of many genes in bacteria in responses to changes in their environment. Moreover, bacteria have evolved several elaborate and elegant variations on the attenuation theme, mainly based on the mechanism used to control formation of the RNA structures that signal RNA polymerase to pause or terminate transcription.

Original language	English
Title of host publication	Encyclopedia of Biological Chemistry
Subtitle of host publication	Second Edition
Publisher	Elsevier Inc.
Pages	360-364
Number of pages	5
ISBN (Electronic)	9780123786319
ISBN (Print)	9780123786302
DOIs	https://doi.org/10.1016/B978-0-12-378630-2.00270-X
State	Published - Feb 15 2013

Keywords

Attenuation
Codon
Gene regulation
Ribosome
RNA structure
RNA-binding protein
Termination
Transcription
Tryptophan

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10.1016/B978-0-12-378630-2.00270-X

Cite this

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abstract = "Transcription attenuation is defined as any mechanism that utilizes transcriptional pausing or termination to control expression of downstream genes. This mechanism of regulation is used to control expression of many genes in bacteria in responses to changes in their environment. Moreover, bacteria have evolved several elaborate and elegant variations on the attenuation theme, mainly based on the mechanism used to control formation of the RNA structures that signal RNA polymerase to pause or terminate transcription.",

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AB - Transcription attenuation is defined as any mechanism that utilizes transcriptional pausing or termination to control expression of downstream genes. This mechanism of regulation is used to control expression of many genes in bacteria in responses to changes in their environment. Moreover, bacteria have evolved several elaborate and elegant variations on the attenuation theme, mainly based on the mechanism used to control formation of the RNA structures that signal RNA polymerase to pause or terminate transcription.

KW - Attenuation

KW - Codon

KW - Gene regulation

KW - Ribosome

KW - RNA structure

KW - RNA-binding protein

KW - Termination

KW - Transcription

KW - Tryptophan

UR - https://www.scopus.com/pages/publications/85042756370

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DO - 10.1016/B978-0-12-378630-2.00270-X

M3 - Chapter

AN - SCOPUS:85042756370

SN - 9780123786302

SP - 360

EP - 364

BT - Encyclopedia of Biological Chemistry

PB - Elsevier Inc.

ER -

Gene Expression in Bacterial Systems: The trp Operon and Attenuation

Abstract

Keywords

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