Fungal DNA detected in blood samples of patients who received contaminated methylprednisolone injections reveals increased complexity of causative agents

Yanan Zhao; Emilian Armeanu; Richard DiVerniero; Terri A. Lewis; Richard C. Dobson; Dimitrios P. Kontoyiannis; Emmanuel Roilides; Thomas J. Walsh; David S. Perlina

doi:10.1128/JCM.00854-14

Fungal DNA detected in blood samples of patients who received contaminated methylprednisolone injections reveals increased complexity of causative agents

Yanan Zhao
, Emilian Armeanu
, Richard DiVerniero
, Terri A. Lewis
, Richard C. Dobson
, Dimitrios P. Kontoyiannis
, Emmanuel Roilides
, Thomas J. Walsh
, David S. Perlina

Pharmacy

SICC LLC
Premier Orthopaedic Associates
National Changhua University of Education
2117 Buffalo Rd.
Exserohilum Meningitis Research Consortium
University of Texas MD Anderson Cancer Center
Aristotle University of Thessaloniki
New York Presbyterian Hospital

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Using Exserohilum rostratum-specific and panfungal real-time PCR, we studied 24 blood samples and 2 synovial fluid specimens from 20 patients with persistent or worsening pain following injections of contaminated methylprednisolone. Seven blood specimens from 6 patients were significantly positive for fungal DNA by panfungal PCR, with multiple fungal species identified.

Original language	English
Pages (from-to)	2212-2215
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	52
Issue number	6
DOIs	https://doi.org/10.1128/JCM.00854-14
State	Published - Jun 2014

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Zhao, Y., Armeanu, E., DiVerniero, R., Lewis, T. A., Dobson, R. C., Kontoyiannis, D. P., Roilides, E., Walsh, T. J., & Perlina, D. S. (2014). Fungal DNA detected in blood samples of patients who received contaminated methylprednisolone injections reveals increased complexity of causative agents. Journal of Clinical Microbiology, 52(6), 2212-2215. https://doi.org/10.1128/JCM.00854-14

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title = "Fungal DNA detected in blood samples of patients who received contaminated methylprednisolone injections reveals increased complexity of causative agents",

abstract = "Using Exserohilum rostratum-specific and panfungal real-time PCR, we studied 24 blood samples and 2 synovial fluid specimens from 20 patients with persistent or worsening pain following injections of contaminated methylprednisolone. Seven blood specimens from 6 patients were significantly positive for fungal DNA by panfungal PCR, with multiple fungal species identified.",

author = "Yanan Zhao and Emilian Armeanu and Richard DiVerniero and Lewis, \{Terri A.\} and Dobson, \{Richard C.\} and Kontoyiannis, \{Dimitrios P.\} and Emmanuel Roilides and Walsh, \{Thomas J.\} and Perlina, \{David S.\}",

year = "2014",

month = jun,

doi = "10.1128/JCM.00854-14",

language = "English",

volume = "52",

pages = "2212--2215",

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Zhao, Y, Armeanu, E, DiVerniero, R, Lewis, TA, Dobson, RC, Kontoyiannis, DP, Roilides, E, Walsh, TJ & Perlina, DS 2014, 'Fungal DNA detected in blood samples of patients who received contaminated methylprednisolone injections reveals increased complexity of causative agents', Journal of Clinical Microbiology, vol. 52, no. 6, pp. 2212-2215. https://doi.org/10.1128/JCM.00854-14

TY - JOUR

T1 - Fungal DNA detected in blood samples of patients who received contaminated methylprednisolone injections reveals increased complexity of causative agents

AU - Zhao, Yanan

AU - Armeanu, Emilian

AU - DiVerniero, Richard

AU - Lewis, Terri A.

AU - Dobson, Richard C.

AU - Kontoyiannis, Dimitrios P.

AU - Roilides, Emmanuel

AU - Walsh, Thomas J.

AU - Perlina, David S.

PY - 2014/6

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AB - Using Exserohilum rostratum-specific and panfungal real-time PCR, we studied 24 blood samples and 2 synovial fluid specimens from 20 patients with persistent or worsening pain following injections of contaminated methylprednisolone. Seven blood specimens from 6 patients were significantly positive for fungal DNA by panfungal PCR, with multiple fungal species identified.

UR - https://www.scopus.com/pages/publications/84901675886

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DO - 10.1128/JCM.00854-14

M3 - Article

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AN - SCOPUS:84901675886

SN - 0095-1137

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EP - 2215

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

IS - 6

ER -

Fungal DNA detected in blood samples of patients who received contaminated methylprednisolone injections reveals increased complexity of causative agents

Abstract

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