Fluctuation anaLysis calculator: A web tool for the determination of mutation rate using Luria-Delbück fluctuation analysis

Brandon M. Hall; Chang Xing Ma; Ping Liang; Keshav K. Singh

doi:10.1093/bioinformatics/btp253

Fluctuation anaLysis calculator: A web tool for the determination of mutation rate using Luria-Delbück fluctuation analysis

Brandon M. Hall
, Chang Xing Ma
, Ping Liang
, Keshav K. Singh

Department of Biostatistics

Roswell Park Cancer Institute
Brock University

Research output: Contribution to journal › Article › peer-review

316 Scopus citations

Abstract

The program Fluctuation AnaLysis CalculatOR (FALCOR) is a web tool designed for use with Luria-Delbrück fluctuation analysis to calculate the frequency and rate from various mutation assays in bacteria and yeast. Three calculation methods are available through this program: (i) Ma-Sandri-Sarkar Maximum Likelihood Estimator (MSS-MLE) method, (ii) Lea-Coulson method of the median (LC) and (iii) frequency.

Original language	English
Pages (from-to)	1564-1565
Number of pages	2
Journal	Bioinformatics
Volume	25
Issue number	12
DOIs	https://doi.org/10.1093/bioinformatics/btp253
State	Published - 2009

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abstract = "The program Fluctuation AnaLysis CalculatOR (FALCOR) is a web tool designed for use with Luria-Delbr{\"u}ck fluctuation analysis to calculate the frequency and rate from various mutation assays in bacteria and yeast. Three calculation methods are available through this program: (i) Ma-Sandri-Sarkar Maximum Likelihood Estimator (MSS-MLE) method, (ii) Lea-Coulson method of the median (LC) and (iii) frequency.",

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AB - The program Fluctuation AnaLysis CalculatOR (FALCOR) is a web tool designed for use with Luria-Delbrück fluctuation analysis to calculate the frequency and rate from various mutation assays in bacteria and yeast. Three calculation methods are available through this program: (i) Ma-Sandri-Sarkar Maximum Likelihood Estimator (MSS-MLE) method, (ii) Lea-Coulson method of the median (LC) and (iii) frequency.

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Fluctuation anaLysis calculator: A web tool for the determination of mutation rate using Luria-Delbück fluctuation analysis

Abstract

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