Femtogram-scale photothermal spectroscopy of explosive molecules on nanostrings

T. S. Biswas; N. Miriyala; C. Doolin; X. Liu; T. Thundat; J. P. Davis

doi:10.1021/ac503318e

Femtogram-scale photothermal spectroscopy of explosive molecules on nanostrings

T. S. Biswas
, N. Miriyala
, C. Doolin
, X. Liu
, T. Thundat
, J. P. Davis

Department of Chemical and Biological Engineering

University of Alberta

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

We demonstrate detection of femtogram-scale quantities of the explosive molecule 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) via combined nanomechanical photothermal spectroscopy and mass desorption. Photothermal spectroscopy provides a spectroscopic fingerprint of the molecule, which is unavailable using mass adsorption/desorption alone. Our measurement, based on thermomechanical measurement of silicon nitride nanostrings, represents the highest mass resolution ever demonstrated via nanomechanical photothermal spectroscopy. This detection scheme is quick, label-free, and is compatible with parallelized molecular analysis of multicomponent targets.

Original language	English
Pages (from-to)	11368-11372
Number of pages	5
Journal	Analytical Chemistry
Volume	86
Issue number	22
DOIs	https://doi.org/10.1021/ac503318e
State	Published - Nov 18 2014

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10.1021/ac503318e

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title = "Femtogram-scale photothermal spectroscopy of explosive molecules on nanostrings",

abstract = "We demonstrate detection of femtogram-scale quantities of the explosive molecule 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) via combined nanomechanical photothermal spectroscopy and mass desorption. Photothermal spectroscopy provides a spectroscopic fingerprint of the molecule, which is unavailable using mass adsorption/desorption alone. Our measurement, based on thermomechanical measurement of silicon nitride nanostrings, represents the highest mass resolution ever demonstrated via nanomechanical photothermal spectroscopy. This detection scheme is quick, label-free, and is compatible with parallelized molecular analysis of multicomponent targets.",

author = "Biswas, \{T. S.\} and N. Miriyala and C. Doolin and X. Liu and T. Thundat and Davis, \{J. P.\}",

note = "Publisher Copyright: {\textcopyright} 2014 American Chemical Society.",

year = "2014",

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doi = "10.1021/ac503318e",

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T1 - Femtogram-scale photothermal spectroscopy of explosive molecules on nanostrings

AU - Biswas, T. S.

AU - Miriyala, N.

AU - Doolin, C.

AU - Liu, X.

AU - Thundat, T.

AU - Davis, J. P.

PY - 2014/11/18

Y1 - 2014/11/18

N2 - We demonstrate detection of femtogram-scale quantities of the explosive molecule 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) via combined nanomechanical photothermal spectroscopy and mass desorption. Photothermal spectroscopy provides a spectroscopic fingerprint of the molecule, which is unavailable using mass adsorption/desorption alone. Our measurement, based on thermomechanical measurement of silicon nitride nanostrings, represents the highest mass resolution ever demonstrated via nanomechanical photothermal spectroscopy. This detection scheme is quick, label-free, and is compatible with parallelized molecular analysis of multicomponent targets.

AB - We demonstrate detection of femtogram-scale quantities of the explosive molecule 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) via combined nanomechanical photothermal spectroscopy and mass desorption. Photothermal spectroscopy provides a spectroscopic fingerprint of the molecule, which is unavailable using mass adsorption/desorption alone. Our measurement, based on thermomechanical measurement of silicon nitride nanostrings, represents the highest mass resolution ever demonstrated via nanomechanical photothermal spectroscopy. This detection scheme is quick, label-free, and is compatible with parallelized molecular analysis of multicomponent targets.

UR - https://www.scopus.com/pages/publications/84922569847

U2 - 10.1021/ac503318e

DO - 10.1021/ac503318e

M3 - Article

C2 - 25329453

AN - SCOPUS:84922569847

SN - 0003-2700

VL - 86

SP - 11368

EP - 11372

JO - Analytical Chemistry

JF - Analytical Chemistry

IS - 22

ER -

Femtogram-scale photothermal spectroscopy of explosive molecules on nanostrings

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