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Evaluation of an alternating current plasma emission detector for high-performance liquid chromatography

  • University of Massachusetts Lowell

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The details of construction and operation of an alternating current plasma (ACP) detector supported with helium gas for reversed-phase high-performance liquid chromatography is described. The system is evaluated as a selective detector for the determination of organomercury compounds. The chromatographic eluent is introduced into the plasma by means of a frit nebulizer and the plasma can tolerate the nebulization of 100% methanol without extinguishment. Detection limits of methylmercury chloride and ethylmercury chloride were found to be 4.5 and 2.2 ng Hg/sec, respectively. In the nanogram to microgram mass range studied the precision was found to be less than 10% (relative standard deviation). The deduction of organomercurials in complex sample matrices elustrates the selectivity of the ACP detector.

Original languageEnglish
Pages (from-to)159-166
Number of pages8
JournalJournal of Chromatography A
Volume513
Issue numberC
DOIs
StatePublished - 1990

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